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prasugrel

A novel platelet inhibitor approved for the reduction of thrombotic cardiovascular events in patients with acute coronary syndrome. Prasugrel… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Background and Purpose— The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for… Expand
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Review
2017
Review
2017
Dual antiplatelet therapy with aspirin and a P2Y12 inhibitor is the treatment of choice for the prevention of atherothrombotic… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The effect of intensified platelet inhibition for patients with unstable angina or myocardial infarction without ST… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Mechanical reperfusion with stenting for ST-elevation myocardial infarction (STEMI) is supported by dual antiplatelet… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet… Expand
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Review
2009
Review
2009
BACKGROUND Proton-pump inhibitors (PPIs) are often prescribed in combination with thienopyridines. Conflicting data exist as to… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Patients with diabetes mellitus (DM) are at high risk for recurrent cardiovascular events after acute coronary… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of treatment to prevent thrombotic… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The increasing use of higher-than-approved doses of clopidogrel in clinical practice is based in part on the desire… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Thienopyridines are metabolized to active metabolites that irreversibly inhibit the platelet P2Y(12) adenosine… Expand
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