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ppGpp synthetase

 
National Institutes of Health

Papers overview

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2017
2017
Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli
Nucleotide excision repair in Escherichia coli is stimulated by transcription, specifically in the transcribed strand. Previously… Expand
Review
2011
Review
2011
Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants.
The hyperphosphorylated guanine ribonucleotide ppGpp mediates the stringent response in bacteria. Biochemical and genetic studies… Expand
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2006
2006
The effect of intracellular ppGpp levels on glutamate and lysine overproduction in Escherichia coli.
Although the enhancement of amino-acid synthesis by guanosine-3',5'-tetraphosphate (ppGpp) is well known, the effect of… Expand
Highly Cited
2005
Highly Cited
2005
Effective symbiosis between Rhizobium etli and Phaseolus vulgaris requires the alarmone ppGpp.
The symbiotic interaction between Rhizobium etli and Phaseolus vulgaris, the common bean plant, ultimately results in the… Expand
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Highly Cited
2004
Highly Cited
2004
Structural Basis for Transcription Regulation by Alarmone ppGpp
Guanosine-tetraphosphate (ppGpp) is a major regulator of stringent control, an adaptive response of bacteria to amino acid… Expand
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Highly Cited
2004
Highly Cited
2004
Delayed‐relaxed response explained by hyperactivation of RelE
Escherichia coli encodes two rel loci, both of which contribute to the control of synthesis of macromolecules during amino acid… Expand
2002
2002
Enterobacter cloacae rpoS promoter and gene organization
The upstream region of theEnterohacter cloacae strain CECT960rpoS gene was sequenced. AnIS10R element was found within thenlpD… Expand
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Highly Cited
2001
Highly Cited
2001
Binding of the Transcription Effector ppGpp to Escherichia coli RNA Polymerase Is Allosteric, Modular, and Occurs Near the N Terminus of the β′-Subunit*
Among the prokaryotae, the nucleotide ppGpp is a second messenger of physiological stress and starvation. The target of ppGpp is… Expand
Highly Cited
1995
Highly Cited
1995
Evidence for a ppGpp‐binding site on Escherichia coli RNA polymerase: proximity relationship with the rifampicin‐binding domain
On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is… Expand
Highly Cited
1993
Highly Cited
1993
Guanosine tetraphosphate inhibits protein synthesis in vivo. A possible protective mechanism for starvation stress in Escherichia coli.
Guanosine 3',5'-bispyrophosphate (ppGpp) accumulates in bacteria in response to either amino acid or energy source starvation… Expand
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