positive regulation of protein phosphatase type 2B activity

Known as: up-regulation of protein phosphatase type 2B activity, up regulation of calcineurin activity, up regulation of protein phosphatase type 2B activity 
Any process that activates or increases the activity of the enzyme protein phosphatase type 2B. [GOC:mah]
National Institutes of Health

Papers overview

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2014
2014
A recurrent activating PLCG1 mutation in cardiac angiosarcomas increases apoptosis resistance and invasiveness of endothelial cells.
Primary cardiac angiosarcomas are rare tumors with unfavorable prognosis. Pathogenic driver mutations are largely unknown. We… (More)
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2011
2011
The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection.
Allograft rejection remains a major limitation to successful solid organ transplantation. Here, we investigated the biosynthesis… (More)
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2011
2011
Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation.
BACKGROUND Ginseng is a medicinal plant used widely in Asia that has gained popularity in the West during the past decade… (More)
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2010
2010
Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity.
Expression of an activated form of calcineurin in skeletal muscle selectively up-regulates slow-fiber-specific gene expression… (More)
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2007
2007
Mechanisms of Ca2+-dependent calcineurin activation in mechanical stretch-induced hypertrophy.
Pressure overload is the major stimulus for cardiac hypertrophy. Accumulating evidence suggests an important role for calcium… (More)
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Highly Cited
2005
Highly Cited
2005
Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle.
We examined the transcriptional signaling cascade involved in the changes of mitochondrial biogenesis and mitochondrial function… (More)
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2001
2001
Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.
Calcineurin, a Ca(2+)/calmodulin-dependent Ser/Thr phosphatase (protein phosphatase 2B), plays a critical role in IL-2 production… (More)
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2000
2000
T Cell Receptor–Induced Calcineurin Activation Regulates T Helper Type 2 Cell Development by Modifying the Interleukin 4 Receptor Signaling Complex
The activation of downstream signaling pathways of both T cell receptor (TCR) and interleukin 4 receptor (IL-4R) is essential for… (More)
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1999
1999
Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin.
Ca(2+)-mobilizing compounds such as the Ca(2+) ionophore A23187 or the endoplasmic reticulum Ca(2+) ATPase inhibitor thapsigargin… (More)
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1998
1998
Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation.
Glucocorticoids appear to participate in apoptosis of unselected CD4(+)CD8(+) thymocytes. Activation of Ca2+-independent novel… (More)
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