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polytuftsin

Known as: L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-, homopolymer, tuftsin polymer 
National Institutes of Health

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PolymersTuftsin

Papers overview

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2009
2009
Synthesis of a new carrier for immunization: polytuftsin. Two examples of its use with peptides selected in the hepatitis B surface antigen.
Sequential poly(Arg-Thr-Lys-Pro) consisting mainly of the repeat of tuftsin Thr-Lys-Pro-Arg was synthesized by condensing the p… 
2006
2006
Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: comparative study of the conformation of a Herpes simplex virus glycoprotein gD-1 epitope in the free…
Synthetic carriers play an important role in immunogen presentation, due to their ability of inducing improved and specific… 
1999
1999
Potentiation of Immune Response against the RESA Peptides of Plasmodium falciparum by Incorporating a Universal T‐Cell Epitope (CS. T3) and an Immunomodulator (Polytuftsin), and Delivery through…
Synthetic peptides representing repeat sequences of ring‐infected erythrocyte surface antigen (RESA) of Plasmodium falciparum… 
1999
1999
Correlation of T‐Cell Response and Lymphokine Profile with RESA Peptides of Plasmodium falciparum Containing a Universal T‐Cell Epitope and an Immunopotentiator, Polytuftsin
Two RESA repeat sequences, (EENVEHDA)2 and (DDEHVEEPTVA)2, were chemically linked to a universal T‐cell epitope, CS.T3 and… 
1998
1998
Construction of chimeric immunogens: Bioactive fragment of human IL-1β or polytuftsin (PT) capable of eliciting immune responses to HIV peptides
In this study, we have examined the effect of linking of bloactive fragment of human IL-1β (163–171) or polytuftsin (PT, a… 
1995
1995
Polytuftsin: its possible effects and mechanism during macrophage activation.
1994
1994
Dituftsin and polytuftsin induce an anti-peptide IgG response to non-immunogenic peptides in mice.
The effect of covalently attaching multiple forms of the immunomodulating tetrapeptide tuftsin to normally non-immunogenic… 
1994
1994
Construction of a synthetic immunogen: use of the natural immunomodulator polytuftsin in malaria vaccines against RESA antigen of Plasmodium falciparum.
1992
1992
Synthesis and properties of peptide fragments of the S-region of the surface protein of the heptatitis B virus
A peptide fragment with the 140–146 sequence of the main component of the surrace protein of the hepatitis B virus (HBsAG) and a… 
1991
1991
[Use of synthetic carriers and adjuvants for increasing the immunogenicity of a synthetic peptide from the CS-protein of Plasmodium falciparum].
In order to increase immunogenicity of the peptide (NANP)3, we have prepared a large set of fully synthetic constructions based… 
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