polysialic acid

Known as: POLYSIALIC, polySia 
A highly negative-charged carbohydrate composed of a linear polymer of alpha 2,8-linked sialic acid residue with potential immunotherapeutic activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
0204019792018

Papers overview

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Highly Cited
2005
Highly Cited
2005
Poly-alpha2,8-sialic acid (polySia) is a unique modification of the neural cell adhesion molecule, NCAM, tightly associated with… (More)
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Highly Cited
2000
Highly Cited
2000
Functional properties of the neural cell adhesion molecule (NCAM) are strongly influenced by polysialylation. We used gene… (More)
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Highly Cited
1996
Highly Cited
1996
Transplantation studies have been used to show that tangential migration of olfactory bulb interneuron precursors is retarded in… (More)
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Highly Cited
1996
Highly Cited
1996
The alpha-2,8-linked polysialic acid (PSA) modification of the neural cell adhesion molecule (NCAM) modulates morphogenetic cell… (More)
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Highly Cited
1994
Highly Cited
1994
The mutation of N-CAM in mice produces a phenotype dominated by an undersized olfactory bulb and accumulation of precursors in… (More)
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Highly Cited
1994
Highly Cited
1994
Removal of polysialic acid (PSA) from N-CAM during the time when chick motoneuron axons are segregating into target-specific… (More)
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Highly Cited
1992
Highly Cited
1992
The influence of polysialic acid (PSA) on the neural cell adhesion molecule on motoneuron outgrowth and pathway formation was… (More)
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Highly Cited
1991
Highly Cited
1991
We have proposed previously that the polysialic acid (PSA) moiety of NCAM can influence membrane-membrane apposition, and thereby… (More)
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Highly Cited
1990
Highly Cited
1990
The role of polysialic acid (PSA) during initial innervation of chick muscle was examined. Previously, the adhesion molecules L1… (More)
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Highly Cited
1990
Highly Cited
1990
We have used monolayers of control 3T3 cells and 3T3 cells transfected with a cDNA encoding human N-CAM as a culture substrate… (More)
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