Sialic Acids

Known as: Acids, Sialic, N-Acetylneuraminic Acids, Acids, N-Acetylneuraminic 
A group of naturally occurring N-and O-acyl derivatives of the deoxyamino sugar neuraminic acid. They are ubiquitously distributed in many tissues.
National Institutes of Health

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2,3-difluorosialic acid9-O-lactoyl-N-acetylneuraminic acidMCC-257N acetylneuraminate
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In BloodProcess of secretionSialateSialic Acid Assay
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Papers overview

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Review
2010
Review
2010
Advances in the biology and chemistry of sialic acids.
Sialic acids are a subset of nonulosonic acids, which are nine-carbon alpha-keto aldonic acids. Natural existing sialic acid… (More)
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Highly Cited
2008
Highly Cited
2008
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1.
Klotho is a mammalian senescence-suppression protein that has homology with glycosidases. The extracellular domain of Klotho is… (More)
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Review
2004
Review
2004
Diversity of microbial sialic acid metabolism.
Sialic acids are structurally unique nine-carbon keto sugars occupying the interface between the host and commensal or pathogenic… (More)
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Highly Cited
2004
Highly Cited
2004
Sialic acids: fascinating sugars in higher animals and man.
Sialic acids are acidic monosaccharides, which are among the most important molecules of higher animals, and occur in some… (More)
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Review
2001
Review
2001
Siglecs, sialic acids and innate immunity.
Siglecs are members of the Ig superfamily that bind to sialic acid (Sia) and are mainly expressed by cells of the hematopoietic… (More)
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Review
2000
Review
2000
Achievements and challenges of sialic acid research
Sialic acids are one of the most important molecules of life, since they occupy the terminal position on macromolecules and cell… (More)
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Review
1998
Review
1998
Structure, function and metabolism of sialic acids
Sialic acids represent a family of sugar molecules with an unusual and highly variable chemical structure that are found mostly… (More)
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Review
1997
Review
1997
Sialic acids as ligands in recognition phenomena.
  • Ajit Varki
  • FASEB journal : official publication of the…
  • 1997
The sialic acids are acidic monosaccharides typically found at the outermost ends of the sugar chains of animal glycoconjugates… (More)
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Highly Cited
1988
Highly Cited
1988
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid
The three-dimensional structures of influenza virus haemagglutinins complexed with cell receptor analogues show sialic acids… (More)
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Highly Cited
1959
Highly Cited
1959
The thiobarbituric acid assay of sialic acids.
Members of the sialic acid family of compounds occur in a variety of tissues and body fluids (la, 2) and in bacteria (3… (More)
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