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polyhemoglobin
Known as:
poly Hb
National Institutes of Health
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Hemoglobin
Papers overview
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Review
2009
Review
2009
Nanobiotechnology for hemoglobin-based blood substitutes.
Thomas Ming Swi Chang
Critical care clinics
2009
Corpus ID: 19371785
2009
2009
Extraction of Erythrocyte Enzymes for the Preparation of Polyhemoglobin-catalase-superoxide Dismutase
Jingsong Gu
,
T. Chang
Artificial cells, blood substitutes, and…
2009
Corpus ID: 2821919
In sustained severe ischemia, reperfusion with oxygen carriers may result in ischemia-reperfusion injuries because of the release…
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2007
2007
Polyhemoglobin-Fibrinogen: A Novel Oxygen Carrier with Platelet-Like Properties in a Hemodiluted Setting
N. Wong
,
T. Chang
Artificial cells, blood substitutes, and…
2007
Corpus ID: 32725057
Polyhemoglobin (polyHb) is currently being assessed in phase III trials under various formulations. At present, none contain…
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Highly Cited
2002
Highly Cited
2002
CROSS-LINKED POLYHEMOGLOBIN-SUPEROXIDE DISMUTASE-CATALASE SUPPLIES OXYGEN WITHOUT CAUSING BLOOD BRAIN BARRIER DISRUPTION OR BRAIN EDEMA IN A RAT MODEL OF TRANSIENT GLOBAL BRAIN ISCHEMIA-REPERFUSION
D. Powanda
,
T. Chang
Artificial cells, blood substitutes, and…
2002
Corpus ID: 30894203
In strokes, myocardial infarctions, severe sustained hemorrhagic shock, and donor organs, inadequate blood supply results in lack…
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1995
1995
Superoxide dismutase and catalase cross-linked to polyhemoglobin reduces methemoglobin formation in vitro.
E. A. Quebec
,
T. Chang
Artificial cells, blood substitutes, and…
1995
Corpus ID: 9906677
Superoxide dismutase (SOD) and catalase (CAT) were evaluated for their ability to reduce methemoglobin formation in chemically…
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1992
1992
Immunological effects of hemoglobin, encapsulated hemoglobin, polyhemoglobin and conjugated hemoglobin using different immunization schedules.
T. Chang
,
C. Lister
,
Nishiya
,
R. Varma
Biomaterials Artificial Cells and Immobilization…
1992
Corpus ID: 25591013
Repeated subcutaneous immunizing injections into rats of Freund's adjuvant containing rat hemoglobin or o-raffinose rat…
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1986
1986
Serum Antibody Titers in Rats Receiving Repeated Small Subcutaneous Injections of Hemoglobin or Polyhemoglobin: A Preliminary Report
C.M. Hertzman
,
P. Keipert
,
T. Chang
International Journal of Artificial Organs
1986
Corpus ID: 40387037
Cross-linking hemoglobin (Hb) into Polyhemoglobin (PolyHb) for use as an artificial blood substitute may affect its antigenicity…
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1984
1984
Preparation and in vitro characteristics of a blood substitute based on pyridoxylated polyhemoglobin.
P. Keipert
,
T. Chang
Applied Biochemistry and Biotechnology
1984
Corpus ID: 26530033
Stroma-free hemoglobin (SFHb) is prepared from outdated blood. Red cells are washed, lysed in hypotonic phosphate buffer, and…
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Highly Cited
1984
Highly Cited
1984
Hemoglobin solution--from tetramer to polymer.
G. Moss
,
S. Gould
,
L. Sehgal
,
H. Sehgal
,
A. Rosen
Surgery
1984
Corpus ID: 22370753
Efforts to produce a clinically acceptable hemoglobin solution that could function as a temporary oxygen carrier have evolved…
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1982
1982
Cross-linked Stroma-free Polyhemoglobin as a Potential Blood Substitute
P. Keipert
,
J. Minkowitz
,
T. Chang
International Journal of Artificial Organs
1982
Corpus ID: 23076518
Stroma-free hemoglobin is prepared from human blood and then cross-linked with glutaraldehyde to produce soluble polyhemoglobin…
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