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polyestradiol phosphate

Known as: polyestradiol phosphate [Chemical/Ingredient], Estradiol Phosphate Polymer, Estra-1,3,5(10)-triene-3,17 diol (17-beta)-, polymer with phosporic acid 
A synthetic long-acting polymer derivative of the female sex hormone estradiol. As the primary, most potent estrogen hormone produced by the ovaries… 
National Institutes of Health

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CYP1A2 protein, humanCYP3A7 protein, humanDrug AllergyHot flushes

Broader (3)

EstradiolEstrogenspolyestradiol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Pharmacokinetics and testosterone suppression of a single dose of polyestradiol phosphate (Estradurin®) in prostatic cancer patients
The pharmacokinetics and endocrine effects of polyestradiol phosphate (PEP; Estradurin®) were studied by determination of the… 
1988
1988
Single Drug Polyestradiol Phosphate Therapy in Pro static Cancer
Serum concentrations of testosterone (T) and estradiol-17β (E2) were analyzed in prostatic cancer patients treated with 160, 240… 
1988
1988
Clinical pharmacology of polyestradiol phosphate
The results of the present studies demonstrate that intramuscular injections of polyestradiol phosphate (PEP) produce not only… 
1987
1987
Plasma concentrations of estradiol and testosterone in single-drug polyestradiol phosphate therapy for prostatic cancer.
To evaluate the appropriate dosage of polyestradiol phosphate (PEP, Estradurin) as single-drug therapy, patients with metastatic… 
1986
1986
Cardiovascular complications of estrogen therapy for nondisseminated prostatic carcinoma. A preliminary report from a randomized multicenter study.
In a prospective multicenter study, 244 men with highly or moderately differentiated prostatic cancer in stage I, II or III… 
1981
1981
Effect of treatment with diethylstilbestrol-polyestradiol phosphate or estramustine phosphate (estracyt) on natural killer cell activity in patients with prostatic cancer.
We evaluated the effect of treatment of patients with prostatic cancer with estramustine phosphate or the combination… 
1980
1980
Use of polyestradiol phosphate and anti‐17β estradiol antibodies for the localization of estrogen receptors in target tissues: A critique
Polyestradiol phosphate (PEP) has been used for localization of estrogen receptors in human carcinoma. The nature of PEP binding… 
Highly Cited
1980
Highly Cited
1980
Comparison of biochemical and histochemical techniques for estrogen receptor analyses in mammary carcinoma
Three histochemical techniques for estrogen binding localization in tissue sections were compared to sucrose density gradient… 
1980
1980
Polyestradiol phosphate and ethinyl estradiol in treatment of prostatic carcinoma.
Polyestradiol phosphate is a polymeric ester of estradiol -17 beta and phosphoric acid. The large molecule has very weak… 
1976
1976
Further studies on the effects of adrenergic, serotonergic and cholinergic drugs on the afternoon surge of plasma prolactin in ovariectomized, estrogen-treated rats.
The involvement of adrenergic, serotonergic and cholinergic mechanisms in the diurnal surge of plasma prolactin (Prl) secretion… 
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