polycystin

 
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Autosomal dominant polycystic kidney disease (ADPKD) gene products polycystin-1 (PC1) and polycystin-2 (PC2) colocalize in the… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in either polycystin-2 (PC2) or polycystin-1 (PC1) proteins cause severe, potentially lethal, kidney disorders and… (More)
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Highly Cited
2003
Highly Cited
2003
Mutations in polycystin 2 (PC2), a Ca(2+)-permeable cation channel, cause autosomal dominant polycystic kidney disease. Whether… (More)
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Highly Cited
2000
Highly Cited
2000
The human kidney is composed of roughly 1.2-million renal tubules that must maintain their tubular structure to function properly… (More)
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Highly Cited
2000
Highly Cited
2000
Autosomal dominant polycystic kidney disease (ADPKD), often caused by mutations in the PKD1 gene, is associated with life… (More)
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Highly Cited
1999
Highly Cited
1999
Polycystic kidney diseases are genetic disorders in which the renal parenchyma is progressively replaced by fluid-filled cysts… (More)
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Highly Cited
1997
Highly Cited
1997
Autosomal dominant polycystic kidney disease (AD-PKD) is predominantly caused by mutations of the gene PKD1, which encodes a… (More)
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Highly Cited
1997
Highly Cited
1997
The primary structure of polycystin predicts a large integral membrane protein with multiple cell recognition motifs, but its… (More)
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Highly Cited
1996
Highly Cited
1996
Polycystin, the product of autosomal dominant polycystic kidney disease (ADPKD) 1 gene (PKD1) is the cardinal member of a novel… (More)
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Highly Cited
1996
Highly Cited
1996
Polycystic kidney disease 1 (PKD1) is the major locus of the common genetic disorder autosomal dominant polycystic kidney disease… (More)
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