pleuromutilin

Known as: Drosophilin B, octahydro-5,8-dihydroxy-4,6,9,10- tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopenta- cycloocten-1(4H)-one 8-glycolate, pleuromutilin [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
OBJECTIVES To investigate the genetic basis of pleuromutilin resistance in porcine methicillin-resistant Staphylococcus aureus… (More)
Is this relevant?
2012
2012
BACKGROUND BC-3781 is an investigational semi-synthetic pleuromutilin antibiotic, which recently finished a clinical Phase 2… (More)
  • table 1
  • table 2
  • table 2
  • table 3
Is this relevant?
2012
2012
BC-3781 is a novel semisynthetic pleuromutilin antimicrobial agent developed as an intravenous and oral therapy for acute… (More)
  • table 1
  • table 2
  • table 2
Is this relevant?
2011
2011
A novel streptogramin A, pleuromutilin, and lincosamide resistance determinant, Vga(E), was identified in porcine methicillin… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Methicillin-resistant Staphylococcus aureus clonal lineage ST398 and methicillin-susceptible lineage ST9 strains have their main… (More)
  • table 1
Is this relevant?
Highly Cited
2007
Highly Cited
2007
New insights into functional flexibility at the peptidyl transferase center (PTC) and its vicinity were obtained by analysis of… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2007
2007
Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in… (More)
Is this relevant?
2006
2006
Retapamulin (SB-275833), the first pleuromutilin to be developed for human topical use, was tested against a selected population… (More)
Is this relevant?
2006
2006
Tiamulin is a pleuromutilin antibiotic that is used in veterinary medicine. The recently published crystal structure of a… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Tiamulin, a prominent member of the pleuromutilin class of antibiotics, is a potent inhibitor of protein synthesis in bacteria… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?