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pleuromutilin

Known as: Drosophilin B, octahydro-5,8-dihydroxy-4,6,9,10- tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopenta- cycloocten-1(4H)-one 8-glycolate, pleuromutilin [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Diterpenes
Pleuromutilin Antibacterial [EPC]retapamulin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Lefamulin: a promising new pleuromutilin antibiotic in the pipeline
ABSTRACT Introduction: Community-acquired bacterial pneumonia (CABP) represents a significant clinical and financial burden… 
2013
2013
Improvement of Daptomycin Production in Streptomyces roseosporus through the Acquisition of Pleuromutilin Resistance
Daptomycin, a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, displays potent activity against a variety of… 
2011
2011
Expanding the pleuromutilin class of antibiotics by de novo chemical synthesis.
New pleuromutilin-like compounds were synthesized in approximately 11 steps from 3-allylcyclopent-2-enone by a strategy featuring… 
Highly Cited
2004
Highly Cited
2004
Decreased susceptibility to tiamulin and valnemulin among Czech isolates of Brachyspira hyodysenteriae.
The agar dilution method was used to investigate the sensitivity to pleuromutilins of 100 isolates of Brachyspira hyodysenteriae… 
2003
2003
A concise synthesis of the tricyclic skeleton of pleuromutilin and a new approach to cycloheptenes.
[reaction: see text] A short synthesis of the tricyclic skeleton of pleuromutilin is reported, featuring an unusually efficient 8… 
1984
1984
Screening for new compounds with antiherpes activity.
1978
1978
The effects of tiamulin, a semisynthetic pleuromutilin derivative, on bacterial polypeptide chain initiation.
Tiamulin, a water-soluble and highly effective semisynthetic derivative of pleuromutilin leads to the formation of… 
1976
1976
Studies on pleuromutilin and some of its derivatives.
A number of derivatives of pleuromutilin (I) and of its degradation product, mutilin (II1, was prepared. The new monotosylation… 
1976
1976
Pleuromutilins. Fermentation, structure and biosynthesis.
Derivatives of pleuromutilin, formed during the fermentation of pleuromutilin, were isolated and their structure determined. 14… 
1975
1975
On the interaction of a lipophilic drug with different sites of rat-liver microsomes. Equilibrium studies with a substituted pleuromutilin.
The binding of the diterpenoid drug 14-deoxy-14-[(2'-diethylamino-ethyl)-mercaptoacetoxy]-dihydromutilin hydrogen fumarate in the… 
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