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plectasin

National Institutes of Health

Papers overview

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2015
2015
A number of pathogenic bacterial strains, such as Staphylococcus aureus, are difficult to kill with conventional antibiotics due… Expand
Highly Cited
2013
Highly Cited
2013
NZ2114, a new variant of plectasin, was overexpressed in Pichia pastoris X-33 via pPICZαA for the first time. The total secreted… Expand
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Highly Cited
2010
Highly Cited
2010
Defining Defensins' Mode of Action Defensins are antimicrobial host defense peptides that play a role in innate immunity. Many… Expand
Highly Cited
2010
Highly Cited
2010
BackgroundHost defence peptides (HDPs), also known as antimicrobial peptides (AMPs), have emerged as potential new therapeutics… Expand
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Highly Cited
2009
Highly Cited
2009
We describe the use of racemic crystallography to determine the X‐ray structure of the natural product plectasin, a potent… Expand
Highly Cited
2009
Highly Cited
2009
ABSTRACT NZ2114 is a novel plectasin derivative with potent activity against gram-positive bacteria, including multiply drug… Expand
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2009
2009
  • B. Matthews
  • Protein science : a publication of the Protein…
  • 2009
  • Corpus ID: 5394370
As protein synthetic techniques become more precise and more routine, racemic crystallography will become a powerful and more… Expand
2009
2009
ABSTRACT Antimicrobial therapy of infections with Staphylococcus aureus can pose a challenge due to slow response to therapy and… Expand
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2008
2008
Animals and plants express endogenous peptide antibiotics called defensins. Defensins show broad-spectrum antimicrobial activity… Expand
Highly Cited
2005
Highly Cited
2005
Animals and higher plants express endogenous peptide antibiotics called defensins. These small cysteine-rich peptides are active… Expand
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