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A number of pathogenic bacterial strains, such as Staphylococcus aureus, are difficult to kill with conventional antibiotics due… Expand NZ2114, a new variant of plectasin, was overexpressed in Pichia pastoris X-33 via pPICZαA for the first time. The total secreted… Expand Defining Defensins' Mode of Action Defensins are antimicrobial host defense peptides that play a role in innate immunity. Many… Expand BackgroundHost defence peptides (HDPs), also known as antimicrobial peptides (AMPs), have emerged as potential new therapeutics… Expand We describe the use of racemic crystallography to determine the X‐ray structure of the natural product plectasin, a potent… Expand ABSTRACT NZ2114 is a novel plectasin derivative with potent activity against gram-positive bacteria, including multiply drug… Expand As protein synthetic techniques become more precise and more routine, racemic crystallography will become a powerful and more… Expand ABSTRACT Antimicrobial therapy of infections with Staphylococcus aureus can pose a challenge due to slow response to therapy and… Expand Animals and plants express endogenous peptide antibiotics called defensins. Defensins show broad-spectrum antimicrobial activity… Expand Animals and higher plants express endogenous peptide antibiotics called defensins. These small cysteine-rich peptides are active… Expand