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platonin

Known as: platonin J 
National Institutes of Health

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Thiazoles

Papers overview

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2012
2012
Platonin mitigates lung injury in a two-hit model of hemorrhage/resuscitation and endotoxemia in rats
BACKGROUND: Traumatic hemorrhagic shock and subsequent resuscitation may promote bacteria translocation and cause endotoxemia, a… 
2011
2011
Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling
Aim:To examine the inhibitory actions of the immunoregulator platonin against proliferation of rat vascular smooth muscle cells… 
2008
2008
Platonin inhibits LPS-induced NF-κB by preventing activation of Akt and IKKβ in human PBMC
Abstract.Objective:Platonin is a potent macrophage-activating agent and an immunomodulator. It has been used to treat trauma… 
2006
2006
Platonin attenuates LPS‐induced CAT‐2 and CAT‐2B induction in stimulated murine macrophages
Background:  Platonin, a cyanine photosensitizing dye, is a potent immunomodulator that suppresses acute inflammation. Platonin… 
2006
2006
Kinetic radical-scavenging activity of platonin, a cyanine photosensitizing dye.
Platonin is known to possess antioxidant activity. However, the kinetics of the radical-scavenging activities of this compound… 
2003
2003
Platonin, a cyanine photosensitizing dye, inhibits pyrogen release and results in antipyresis.
Intravenous injection of the supernatant fluids from human peripheral blood mononuclear cells (PBMC) incubated with… 
2002
2002
Platonin, a photosensitizing dye, improves circulatory failure and mortality in rat models of endotoxemia.
Platonin, a cyanine photosensitizing dye, is a potent macrophage-activating agent and an immunomodulator. In this study, we… 
1991
1991
The effect of photosensitive dye Platonin on juvenile rheumatoid arthritis
Two children with juvenile rheumatoid arthritis (JRA) were given photosensitive dye Platonin in combination with prednisolone… 
1989
1989
B cell suppressing and CD8+ T cell enhancing effects of photosensitive dye platonin in humans.
Platonin is one of the photosensitive dyes of trithiazole pentamethine cyanine. It is used as an effective medicine for… 
1985
1985
Formation of a leakage-type ion pathway in lipid bilayer membranes by divalent cationic cyanine dyes in cooperation with inorganic phosphate. Role of the cyanine dye in uncoupling of oxidative…
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