platelet degranulation

Known as: platelet exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. [GOC:add]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2018
051019672018

Papers overview

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2012
2012
Platelets release numerous bioactive molecules stored in their granules enabling them to exert a wide range of effects on the… (More)
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Highly Cited
2009
Highly Cited
2009
Hepatocyte death results in a sterile inflammatory response that amplifies the initial insult and increases overall tissue injury… (More)
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Highly Cited
2002
Highly Cited
2002
Secretion of platelet granules is necessary for normal hemostasis. Platelet secretion requires soluble N-ethylmaleimide-sensitive… (More)
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Highly Cited
2000
Highly Cited
2000
To characterize the molecular mechanisms of platelet secretion, we focused on the calcium-induced exocytosis of dense core… (More)
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Highly Cited
2000
Highly Cited
2000
On stimulation by strong agonists, platelets release the contents of 3 storage compartments in 2 apparent waves of exocytosis… (More)
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2000
2000
Platelets function by secreting components necessary for primary clot formation. This report describes an in vitro assay that… (More)
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1997
1997
To further characterize the molecular mechanisms of platelet function, we have sought to identify some of the proteins that… (More)
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Highly Cited
1986
Highly Cited
1986
A specific radioimmunoassay for type beta transforming growth factor (TGF-beta) was developed and used to show that human… (More)
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1984
1984
Platelet-derived growth factor (PDGF) is a potent mitogen for many cultured connective tissue cells. It is present in… (More)
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Highly Cited
1976
Highly Cited
1976
Platelet adhesion to natural and artificial surfaces and adhesion-induced aggregation were investigated in vitro using an annular… (More)
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