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platelet degranulation

Known as: platelet exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. [GOC:add]
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Platelets release numerous bioactive molecules stored in their granules enabling them to exert a wide range of effects on the… Expand
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Highly Cited
2012
Highly Cited
2012
Platelets are vital for hemostasis because they release their granule contents in response to vascular damage. Platelet… Expand
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Highly Cited
2009
Highly Cited
2009
Hepatocyte death results in a sterile inflammatory response that amplifies the initial insult and increases overall tissue injury… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The membrane-bound chemokine fractalkine (CX3CL1) is expressed on various cell types such as activated endothelial… Expand
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Highly Cited
2002
Highly Cited
2002
Secretion of platelet granules is necessary for normal hemostasis. Platelet secretion requires soluble N-ethylmaleimide-sensitive… Expand
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Highly Cited
2000
Highly Cited
2000
On stimulation by strong agonists, platelets release the contents of 3 storage compartments in 2 apparent waves of exocytosis… Expand
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Review
2000
Review
2000
The critical role played by platelets in hemostasis, thrombosis, vascular remodeling, and healing is related to their function as… Expand
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Highly Cited
1997
Highly Cited
1997
To further characterize the molecular mechanisms of platelet function, we have sought to identify some of the proteins that… Expand
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1997
1997
In a previous study, we have demonstrated that the platelet adhesive glycoprotein thrombospondin-1 (TSP-1) interacts specifically… Expand
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Highly Cited
1976
Highly Cited
1976
Platelet adhesion to natural and artificial surfaces and adhesion-induced aggregation were investigated in vitro using an annular… Expand
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