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plafibride
Known as:
2-CIMMU
, N-(2-(4-chlorophenoxy)isobutyryl)-N-morpholinomethylurea
An acyl derivative of morpholinomethylurea (MMU) with clofibric acid with antihyperlipidemic activity. In trials plafibride showed better gastric…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (3)
Clofibric Acid
Hypolipidemic Agents
Platelet Aggregation Inhibitors
analogs & derivatives
Papers overview
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1981
1981
Toxicological studies of plafibride. Part 3: Study of teratogenic activity in rats and rabbits.
C. Sanfeliu
,
J. Zapatero
,
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 7715043
Teratological studies of N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104) were carried out in rats…
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1981
1981
Pharmacological activities and side effects of plafibride.
J. Gras
,
N. Basi
,
+7 authors
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 11770116
This paper reports on pharmacological properties of N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethyl-urea (plafibride, ITA…
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1981
1981
Double-blind study on the activity of plafibride in the treatment of type IV hyperlipoproteinemia.
I. Ferreira
,
A. del Río
,
N. Gonzalez-Viejo
,
B. Vicéns
Arzneimittel-Forschung
1981
Corpus ID: 23145355
The effects of a new drug, N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104), were studied in a…
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1981
1981
Plafibride: clinical trial of a new platelet antiaggregating agent.
J. Olivella
,
B. Vicéns
Arzneimittel-Forschung
1981
Corpus ID: 21627058
A clinical study with a new anti-aggregant preparation; N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA…
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1981
1981
Pharmacokinetic approach of plafibride in rat.
D. Zapatero
,
J. Vilageliu
,
A. Torres
,
J. Ribalta
,
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 32310259
The serum concentration of N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104) and its metabolites was…
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1981
1981
Bioavailability of plafibride in healthy volunteers.
E. Santaniello
,
F. Conti
,
J. Vilageliu
,
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 43475814
The pharmacokinetics of N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104) in rats, and its…
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1981
1981
Bacterial mutation test on plafibride.
M. Richold
,
E. Jones
Arzneimittel-Forschung
1981
Corpus ID: 12265334
N-2-(p-Chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104) was tested for mutagenic activity of the Ames…
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1981
1981
Plafibride tolerance trial at increasing doses in healthy volunteers.
J. Dalmau
,
B. Vicéns
,
J. Zapatero
,
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 31410189
Tolerance of N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride ITA 104), was studied in a group of healthy…
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1981
1981
Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit.
L. Bruseghini
,
J. Vilageliu
,
J. Freixes
Arzneimittel-Forschung
1981
Corpus ID: 25454632
N-2-(p-Chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104) is an acyl derivative of morpholinomethylurea (MMU…
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1981
1981
Toxicological studies of plafibride. Part 4: Interaction of plafibride with other drugs.
J. Zapatero
,
N. Basi
,
J. Vilageliu
,
C. Sanfeliu
,
L. Bruseghini
Arzneimittel-Forschung
1981
Corpus ID: 7342558
The possible pharmacological interaction was studied between N-2-(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride…
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