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plY protein, Streptococcus pneumoniae
Known as:
pneumolysin
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1947-2018
0
10
20
30
1947
2017
Related topics
Related topics
2 relations
Broader (2)
Bacterial Proteins
Streptolysins
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
plY protein, Streptococcus pneumoniae
Bacterial Proteins
Streptolysins
Papers overview
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Highly Cited
2005
Highly Cited
2005
Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Sarah J. Tilley
,
Elena V Orlova
,
Robert J C Gilbert
,
P. Andrew
,
Helen R Saibil
Cell
2005
The bacterial toxin pneumolysin is released as a soluble monomer that kills target cells by assembling into large oligomeric…Â
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Highly Cited
2005
Highly Cited
2005
Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.
Annemarie M. C. van Rossum
,
Elena S. Lysenko
,
Jeffrey N Weiser
Infection and immunity
2005
Nasopharyngeal colonization is the first step in the interaction between Streptococcus pneumoniae (the pneumococcus) and its…Â
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Highly Cited
2004
Highly Cited
2004
Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov.
Judy C Arbique
,
Claire Poyart
,
+7 authors
Richard R. Facklam
Journal of clinical microbiology
2004
We have identified an unusual group of viridans group streptococci that resemble Streptococcus pneumoniae. DNA-DNA homology…Â
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Highly Cited
2004
Highly Cited
2004
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis.
Carlos J Orihuela
,
Geli Gao
,
Kevin P. Francis
,
Jun Yu
,
Elaine I Tuomanen
The Journal of infectious diseases
2004
We assessed the ability of Streptococcus pneumoniae mutants deficient in either choline binding protein A (CbpA), pneumolysin…Â
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Highly Cited
2003
Highly Cited
2003
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.
Richard Malley
,
Philipp Henneke
,
+7 authors
Douglas T Golenbock
Proceedings of the National Academy of Sciences…
2003
Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease worldwide. Fragments of the cell wall and the…Â
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Highly Cited
2001
Highly Cited
2001
Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR.
Chris Corless
,
Michael D Guiver
,
Ray Borrow
,
Valerie Edwards-Jones
,
A J Fox
,
E. B. Kaczmarski
Journal of clinical microbiology
2001
A single-tube 5' nuclease multiplex PCR assay was developed on the ABI 7700 Sequence Detection System (TaqMan) for the detection…Â
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Highly Cited
2001
Highly Cited
2001
Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA.
Adebayo Ogunniyi
,
M C Woodrow
,
Jan T. Poolman
,
J. C. Paton
Infection and immunity
2001
The need for the development of cheap and effective vaccines against pneumococcal disease has necessitated the evaluation of…Â
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Highly Cited
2000
Highly Cited
2000
Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of "Atypical" pneumococci and organisms allied to S. mitis…
A. M. Whatmore
,
Androulla Efstratiou
,
+5 authors
Christopher G Dowson
Infection and immunity
2000
The oral streptococcal group (mitis phylogenetic group) currently consists of nine recognized species, although the group has…Â
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Highly Cited
2000
Highly Cited
2000
Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins.
A. Berry
,
J. C. Paton
Infection and immunity
2000
Although the polysaccharide capsule of Streptococcus pneumoniae has been recognized as a sine qua non of virulence, much recent…Â
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Highly Cited
1989
Highly Cited
1989
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.
A. Berry
,
Janet Yother
,
David E. Briles
,
David Hansman
,
J. C. Paton
Infection and immunity
1989
Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative of Streptococcus pneumoniae. This was…Â
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