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plY protein, Streptococcus pneumoniae

Known as: pneumolysin 
 
National Institutes of Health

Related topics

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2 relations

Broader (2)

Bacterial ProteinsStreptolysins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice.
Pneumococcal infection of the respiratory tract is often secondary to recent influenza virus infection and accounts for much of… Expand
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Highly Cited
2008
Highly Cited
2008
Evolution of Streptococcus pneumoniae and Its Close Commensal Relatives
Streptococcus pneumoniae is a member of the Mitis group of streptococci which, according to 16S rRNA-sequence based phylogenetic… Expand
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Highly Cited
2005
Highly Cited
2005
Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: a longitudinal household study.
BACKGROUND Natural immunity to Streptococcus pneumoniae is thought to be induced by exposure to S. pneumoniae or cross-reactive… Expand
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Highly Cited
2001
Highly Cited
2001
Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR.
A single-tube 5' nuclease multiplex PCR assay was developed on the ABI 7700 Sequence Detection System (TaqMan) for the detection… Expand
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Highly Cited
2001
Highly Cited
2001
The pavA gene of Streptococcus pneumoniae encodes a fibronectin-binding protein that is essential for virulence.
Streptococcus pneumoniae colonizes the nasopharynx in up to 40% of healthy subjects, and is a leading cause of middle ear… Expand
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Highly Cited
2000
Highly Cited
2000
Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins.
Although the polysaccharide capsule of Streptococcus pneumoniae has been recognized as a sine qua non of virulence, much recent… Expand
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Highly Cited
2000
Highly Cited
2000
Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of "Atypical" pneumococci and organisms allied to S. mitis…
The oral streptococcal group (mitis phylogenetic group) currently consists of nine recognized species, although the group has… Expand
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Highly Cited
2000
Highly Cited
2000
Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.
Acquisition of pneumococci is generally from carriers rather than from infected individuals. Therefore, to induce herd immunity… Expand
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Review
1993
Review
1993
Molecular analysis of the pathogenicity of Streptococcus pneumoniae: the role of pneumococcal proteins.
For many years the virulence of Streptococcus pneumoniae has largely been attributed to its antiphagocytic polysaccharide capsule… Expand
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Highly Cited
1989
Highly Cited
1989
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.
Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative of Streptococcus pneumoniae. This was… Expand
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