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plY protein, Streptococcus pneumoniae

Known as: pneumolysin 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
010203019472017

Related topics

Related topics

2 relations

Broader (2)

Bacterial ProteinsStreptolysins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
plY protein, Streptococcus pneumoniae
Bacterial Proteins
Streptolysins

Papers overview

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Highly Cited
2005
Highly Cited
2005
Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
The bacterial toxin pneumolysin is released as a soluble monomer that kills target cells by assembling into large oligomeric… (More)
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Highly Cited
2005
Highly Cited
2005
Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.
Nasopharyngeal colonization is the first step in the interaction between Streptococcus pneumoniae (the pneumococcus) and its… (More)
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Highly Cited
2004
Highly Cited
2004
Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov.
We have identified an unusual group of viridans group streptococci that resemble Streptococcus pneumoniae. DNA-DNA homology… (More)
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Highly Cited
2004
Highly Cited
2004
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis.
We assessed the ability of Streptococcus pneumoniae mutants deficient in either choline binding protein A (CbpA), pneumolysin… (More)
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Highly Cited
2003
Highly Cited
2003
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.
Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease worldwide. Fragments of the cell wall and the… (More)
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Highly Cited
2001
Highly Cited
2001
Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR.
A single-tube 5' nuclease multiplex PCR assay was developed on the ABI 7700 Sequence Detection System (TaqMan) for the detection… (More)
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Highly Cited
2001
Highly Cited
2001
Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA.
The need for the development of cheap and effective vaccines against pneumococcal disease has necessitated the evaluation of… (More)
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Highly Cited
2000
Highly Cited
2000
Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of "Atypical" pneumococci and organisms allied to S. mitis…
The oral streptococcal group (mitis phylogenetic group) currently consists of nine recognized species, although the group has… (More)
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Highly Cited
2000
Highly Cited
2000
Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins.
Although the polysaccharide capsule of Streptococcus pneumoniae has been recognized as a sine qua non of virulence, much recent… (More)
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Highly Cited
1989
Highly Cited
1989
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.
Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative of Streptococcus pneumoniae. This was… (More)
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