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plY protein, Streptococcus pneumoniae

Known as: pneumolysin 
National Institutes of Health

Related topics

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2 relations

Broader (2)

Bacterial ProteinsStreptolysins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae Binds to Lipid Raft Microdomains in Human Corneal Epithelial Cells
Streptococcus pneumoniae (pneumococcus) is an opportunistic bacterial pathogen responsible for causing several human diseases… 
Highly Cited
2012
Highly Cited
2012
Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.
Antibiotics-induced release of the pore-forming virulence factor pneumolysin (PLY) in patients with pneumococcal pneumonia… 
Highly Cited
2010
Highly Cited
2010
Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae.
Highly Cited
2006
Highly Cited
2006
Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia
Objective:Acute respiratory failure is a significant complication of severe pneumococcal pneumonia. In a mouse model, we observed… 
Highly Cited
2001
Highly Cited
2001
Structural Analysis of the Protein/Lipid Complexes Associated with Pore Formation by the Bacterial Toxin Pneumolysin*
Pneumolysin, a major virulence factor of the human pathogen Streptococcus pneumoniae, is a soluble protein that disrupts… 
Highly Cited
1998
Highly Cited
1998
Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae.
The pathogenically important cholesterol-binding pore-forming bacterial "thiol-activated" toxins (TATs) are commonly believed to… 
Review
1997
Review
1997
Biological properties of pneumolysin.
Pneumolysin is a thiol-activated membrane-damaging toxin produced by Streptococcus pneumoniae. The toxin plays a role in… 
Highly Cited
1994
Highly Cited
1994
Modeling the bacterial protein toxin, pneumolysin, in its monomeric and oligomeric form.
Highly Cited
1990
Highly Cited
1990
Demonstration of pneumolysin antibodies in circulating immune complexes - a new diagnoxtic method for pneumococcal pneumonia.
Highly Cited
1947
Highly Cited
1947
COMPARATIVE KINETICS OF HEMOLYSIS INDUCED BY BACTERIAL AND OTHER HEMOLYSINS
A study has been made of the kinetics of lysis induced by various hemolytic agents. The course of bemolysis was followed by… 
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