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pitolisant

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Comparison of modafinil and pitolisant in narcolepsy: a non-inferiority meta-analytical approach
Aim To assess the non-inferiority of pitolisant, a new compound for the relief of excessive daytime sleepiness (EDS) and… 
2020
2020
Splenic Infarction in a Narcoleptic Patient Treated With Methylphenidate, Venlafaxine, and Pitolisant
Methylphenidate, a central stimulant related to amphetamine indicated in attention deficit hyperactivity disorders and narcolepsy… 
2019
2019
P049 Response to pitolisant therapy in patients with difficult to treat hypersomnia
Limited treatment options are available for patients with central hypersomnia, and many patients continue to have significant… 
Review
2017
Review
2017
Human presynaptic receptors.
2017
2017
▼Pitolisant for narcolepsy
▼Pitolisant (Wakix—Bioprojet Pharma) is a new treatment for adults with narcolepsy with or without cataplexy. It was licensed for… 
2016
2016
Exploratory Phase II Trial to Evaluate the Safety and the Antiepileptic Effect of Pitolisant (BF2.649) in Refractory Partial Seizures, Given as Adjunctive Treatment During 3 Months
BackgroundPitolisant (BF2.649) is a nonimidazole histamine 3 receptor antagonist. In previous animal studies, it has been shown… 
2016
2016
Can an early phase clinical pharmacology study replace a thorough QT study? Experience with a novel H3-receptor antagonist/inverse agonist
The objective of the present study was to compare the effects of pitolisant on QTcF interval in a single ascending dose (SAD… 
2016
2016
Action of Pitolisant on the stimulant and rewarding effects of cocaine in mice.
2013
2013
LC-MS/MS method for the determination of pitolisant: application to rat pharmacokinetic and brain penetration studies.
A simple and sensitive LC-MS/MS method was developed and validated for the quantitation of pitolisant, an H3 receptor antagonist… 
2013
2013
Drugs in Clinical Development for Attention-Deficit/Hyperactivity Disorder: Summary and Table
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