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The Vaughan Williams classification has been used widely by clinicians, cardiologists and researchers engaged in antiarrhythmic… Expand BACKGROUND
The relative efficacies of various antiarrhythmic drugs in the treatment of ventricular tachyarrhythmias are not well… Expand To assess the cardiovascular profiles of pirmenol, a new antiarrhythmic drug, and to compare them with those of disopyramide… Expand ESVEM (Electrophysiologic Study Versus Electrocardiographic Monitoring) is an ongoing multicenter trial supported by the National… Expand Using two-stage coronary ligation-, digitalis- and adrenaline-induced canine ventricular arrhythmias, antiarrhythmic effects of… Expand Summary: Pirmenol, a new antiarrhythmic agent, has been studied in the pithed rat and in the sinoatrial (SA) node, atrium… Expand Abstract: Twelve patients having frequent premature ventricular complexes (PVCs) averaging more than 60 per hour received a… Expand Pirmenol (CI-845), a new antiarrhythmic drug, was studied for the first time in humans to establish a minimum effective i.v. dose… Expand The oral form of pirmenol has not been administered to man. Pirmenol was given by mouth to eight patients with chronic, stable… Expand We examined the hemodynamic effects of pirmenol, a new antiarrhythmic drug, for the first time in man. Right and left heart… Expand