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pirmenol
Known as:
2-Pyridinemethanol, alpha-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alpha-phenyl-, monohydrochloride, cis-(+-)-
, cis-alpha-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alpha-phenyl-2-pyridinemethanol monohydrochloride
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Anti-Arrhythmia Agents
Piperidines
Pirmenol:MCnc:Pt:Ser/Plas:Qn
Narrower (1)
pirmenol hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inhibitory effects of class I antiarrhythmic agents on Na+ and Ca2+ currents of human iPS cell-derived cardiomyocytes
Sayaka Yonemizu
,
Keiichiro Masuda
,
+9 authors
I. Hisatome
Regenerative Therapy
2019
Corpus ID: 61810199
1992
1992
Selectivity of class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide for peripheral muscarinic M2 and M3 receptors.
M. Endou
,
Y. Hattori
,
S. Gando
,
M. Kanno
Journal of Cardiovascular Pharmacology
1992
Corpus ID: 45512171
The interactions of the class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide with peripheral muscarinic…
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1991
1991
Pirmenol: An antiarrhythmic drug with unique electrocardiographic features—a double‐blind placebo‐controlled comparison with quinidine
D. Salerno
,
Jeanne Fifield
,
C. Farmer
,
M. Hodges
Clinical Cardiology
1991
Corpus ID: 10702301
Previous reports have stated that pirmenol is a Class IA antiarrhythmic drug that prolongs the QT interval, but did not use…
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1988
1988
Antiarrhythmic plasma concentrations of pirmenol on canine ventricular arrhythmias.
K. Hashimoto
,
K. Watanabe
,
A. Sugiyama
Japanese Journal of Pharmacology
1988
Corpus ID: 19542592
Using two-stage coronary ligation-, digitalis- and adrenaline-induced canine ventricular arrhythmias, antiarrhythmic effects of…
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1986
1986
Electrophysiological and Cardiovascular Effects of Pirmenol, a New Class 1 Antiarrhythmic Drug
I. Dukes
,
E. Williams
,
P. Dennis
Journal of Cardiovascular Pharmacology
1986
Corpus ID: 7676515
Summary: Pirmenol, a new antiarrhythmic agent, has been studied in the pithed rat and in the sinoatrial (SA) node, atrium…
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1985
1985
Antiarrhythmic efficacy of pirmenol in the treatment of premature ventricular complexes.
L. Toivonen
,
M. Nieminen
,
V. Manninen
,
M. Frick
European Heart Journal
1985
Corpus ID: 13064776
We assessed the antiarrhythmic effectiveness, therapeutic plasma concentrations and adverse effects of pirmenol in 16 patients…
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1983
1983
Disposition of Intravenous Pirmenol
S. Sanders
,
J. Nappi
,
R. Foltz
,
J. R. Lutz
,
Jeffrey L. Anderson
Journal of clinical pharmacology
1983
Corpus ID: 22166389
Abstract: Twelve patients having frequent premature ventricular complexes (PVCs) averaging more than 60 per hour received a…
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Highly Cited
1982
Highly Cited
1982
Pirmenol, A New Antiarrhythmic Agent: Initial Study of Efficacy, Safety and Pharmacokinetics
S. Hammill
,
D. Shand
,
P. Routledge
,
M. Hindman
,
J. Baker
,
E. Pritchett
Circulation
1982
Corpus ID: 224729
Pirmenol (CI-845), a new antiarrhythmic drug, was studied for the first time in humans to establish a minimum effective i.v. dose…
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1982
1982
Pirmenol kinetics and effective oral dose
S. Hammill
,
D. Shand
,
+4 authors
E. Pritchett
Clinical pharmacology and therapy
1982
Corpus ID: 6207577
The oral form of pirmenol has not been administered to man. Pirmenol was given by mouth to eight patients with chronic, stable…
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1982
1982
Hemodynamic effects of the antiarrhythmic drug pirmenol
H. Phillips
,
R. Stack
,
+4 authors
E. Pritchett
Clinical pharmacology and therapy
1982
Corpus ID: 1426332
We examined the hemodynamic effects of pirmenol, a new antiarrhythmic drug, for the first time in man. Right and left heart…
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