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pidilizumab

Known as: Immunoglobulin G1, Anti-(Human Programmed Cell Death 1); Humanized Mouse Monoclonal CT-011 Gamma1 Heavy Chain (220-213')-disulfide with Humanized Mouse Monoclonal CT-011 Kappa Light Chain Dimer (226-226'':229-229'')-bisdisulfide, Glycosylated (CT-011 is Expressed in NSO Cells) 
A humanized monoclonal antibody directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities… Expand
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

CT-011MDV9300

Broader (1)

Monoclonal Antibodies
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial.
BACKGROUND Endogenous or iatrogenic antitumour immune responses can improve the course of follicular lymphoma, but might be… Expand
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2014
2014
A Multi-Observatory Inter-Comparison of Line-of-Sight Synoptic Solar Magnetograms
The observed photospheric magnetic field is a crucial parameter for understanding a range of fundamental solar and heliospheric… Expand
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2014
2014
Phase 2, multicenter, safety and efficacy study of pidilizumab in patients with metastatic melanoma.
9001 Background: Pidilizumab (CT-011), a humanized anti PD-1 IgG1k, was studied in two Phase 2 studies in aggressive and indolent… Expand
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Highly Cited
2013
Highly Cited
2013
Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international…
PURPOSE The Programmed Death-1 (PD-1) immune checkpoint pathway may be usurped by tumors, including diffuse large B-cell lymphoma… Expand
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2012
2012
Performance evaluation of small-animal multipinhole μSPECT scanners for mouse imaging
PurposeWe compared the performance of three commercial small-animal μSPECT scanners equipped with multipinhole general purpose… Expand
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2012
2012
Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio).
Heterocyclic aromatic compounds (NSO-HET) have frequently been detected in the environment. Several studies have concluded that… Expand
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2011
2011
Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells
PurposeHeterocyclic aromatic compounds containing nitrogen, sulfur, or oxygen heteroatoms (NSO-HET) have been detected in air… Expand
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2008
2008
Heterocyclic compounds: toxic effects using algae, daphnids, and the Salmonella/microsome test taking methodical quantitative aspects into account.
Heterocyclic aromatic hydrocarbons containing nitrogen, sulfur, or oxygen (NSO-HET), have been detected in air, soil, sewage… Expand
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Highly Cited
2005
Highly Cited
2005
Society of Photo-Optical Instrumentation Engineers
We report here the preliminary results obtained with the multi-conjugate adaptive optics (MCAO) system at the Dunn Solar… Expand
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2000
2000
Immunization of BALB/c mice with killed Neospora caninum tachyzoite antigen induces a type 2 immune response and exacerbates encephalitis and neurological disease.
BALB/c mice were immunized subcutaneously with soluble Neospora caninum tachyzoite antigen (NSO) entrapped in nonionic surfactant… Expand
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