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pidilizumab

Known as: Immunoglobulin G1, Anti-(Human Programmed Cell Death 1); Humanized Mouse Monoclonal CT-011 Gamma1 Heavy Chain (220-213')-disulfide with Humanized Mouse Monoclonal CT-011 Kappa Light Chain Dimer (226-226'':229-229'')-bisdisulfide, Glycosylated (CT-011 is Expressed in NSO Cells) 
A humanized monoclonal antibody directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

CT-011MDV9300

Broader (1)

Monoclonal Antibodies
NCIt Antineoplastic Agent Terminologyantigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Defining the Most Appropriate Primary End Point in Phase 2 Trials of Immune Checkpoint Inhibitors for Advanced Solid Cancers: A Systematic Review and Meta-analysis
Importance Checkpoint inhibitors have a unique mechanism of action that differs from chemotherapy or targeted therapies. The… 
Review
2017
Review
2017
PD-1 and cancer: molecular mechanisms and polymorphisms
The programmed cell death protein 1 (PD-1) is expressed by activated T cells that act as an immunoregulatory molecule, and are… 
Highly Cited
2014
Highly Cited
2014
Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial.
Highly Cited
2014
Highly Cited
2014
A Multi-Observatory Inter-Comparison of Line-of-Sight Synoptic Solar Magnetograms
The observed photospheric magnetic field is a crucial parameter for understanding a range of fundamental solar and heliospheric… 
Highly Cited
2013
Highly Cited
2013
Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international…
PURPOSE The Programmed Death-1 (PD-1) immune checkpoint pathway may be usurped by tumors, including diffuse large B-cell lymphoma… 
Highly Cited
2012
Highly Cited
2012
Performance evaluation of small-animal multipinhole μSPECT scanners for mouse imaging
PurposeWe compared the performance of three commercial small-animal μSPECT scanners equipped with multipinhole general purpose… 
Highly Cited
2012
Highly Cited
2012
Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio).
Highly Cited
2005
Highly Cited
2005
Society of Photo-Optical Instrumentation Engineers
We report here the preliminary results obtained with the multi-conjugate adaptive optics (MCAO) system at the Dunn Solar… 
Highly Cited
2005
Highly Cited
2005
Synthesis, crystal structure and photo-induced DNA cleavage activity of ternary copper(II) complexes of NSO-donor Schiff bases and NN-donor heterocyclic ligands
Highly Cited
2000
Highly Cited
2000
Immunization of BALB/c Mice with Killed Neospora caninum Tachyzoite Antigen Induces a Type 2 Immune Response and Exacerbates Encephalitis and Neurological Disease
ABSTRACT BALB/c mice were immunized subcutaneously with solubleNeospora caninum tachyzoite antigen (NSO) entrapped in nonionic… 
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