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picoprazole

Known as: 1H-Benzimidazole-5-carboxylic acid, 6-methyl-2-(((3-methyl-2-pyridinyl)methyl)sulfinyl)-, methyl ester, 2-((2-(3-methyl)pyridyl-methyl)sulfinyl)-5-methoxycarbonyl-6-methylbenzimidazole 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

2-Pyridinylmethylsulfinylbenzimidazoles

Papers overview

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1990
1990
Influence of condensed benzimidazole derivatives on gastric secretion
Researchers have established [12, 13, 15] that mercapto derivatives of benzimidazoles omeprazole, thymoprazole, picoprazole and… 
1986
1986
Disulfide cross-linking of H,K-ATPase opens Cl- conductance, triggering proton uptake in gastric vesicles. Studies with specific inhibitors.
An S-S cross-linking reagent, Cu2+-o-phenanthroline, increased the 36Cl-/Cl- exchange rate across the hog gastric vesicle… 
1986
1986
Effect of Substituted Benzimidazoles on H+K+ATPase of Isolated Guinea-pig Parietal Cells
Omeprazole, a substituted benzimidazole, has been shown to inhibit gastric acid secretion in vitro and in vivo. In vitro… 
Review
1986
Review
1986
[Effects of gastric proton pump inhibitors on gastric secretion and peptic ulcers].
  • S. Okabe
  • Nihon yakurigaku zasshi. Folia pharmacologica…
  • 1986
  • Corpus ID: 38886111
This is a review article on newly developed antisecretory drugs which are now called proton pump inhibitors. Gastric H+ is… 
1984
1984
Ultrastructure of inhibited parietal cells in the rat.
1984
1984
Microelectrode measurements of K+ and pH in rabbit gastric glands: effect of histamine.
Conventional and liquid ion-exchange microelectrodes sensitive to K+ or pH were used to examine the response of isolated rabbit… 
1984
1984
Parietal cell structure during inhibition of acid secretion.
Acute, pharmacological inhibition of gastric acid secretion is paralleled by a return of the parietal cells to a resting… 
Highly Cited
1983
Highly Cited
1983
Effect of substituted benzimidazoles on acid secretion in isolated and enriched guinea pig parietal cells.
The inhibitory effect of the three benzimidazole derivatives timoprazole, picoprazole, and omeprazole on histamine and dbcAMP… 
Highly Cited
1983
Highly Cited
1983
Inhibition of gastric (H+ + K+)-ATPase by the substituted benzimidazole, picoprazole.
1983
1983
Effects of KCl and insulin on benzimidazole-inhibited canine gastric secretion.
The final step in acid secretion is believed to result from the H+-K+-ATPase-mediated exchange of H+ in the parietal cell, with K… 
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