phthalascidin
National Institutes of Health
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Nous nous sommes tout d'abord familiarise a la synthese de tetrahydroisoquinoleines incorporant des structures heterocycliques…
Ecteinascidin 743 (Et-743) is an exceedingly potent antitumor agent isolated from the marine tunicate Ecteinascidia turbinate. As…
The mechanism of the formation of a key tricyclic lactam intermediate 3 was studied. It was found that the E-form compound 3 was…
A series of totally synthetic molecules that are structurally related to the marine natural product ecteinascidin 743 (Et 743…