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phosphonodifluoromethylphenylalanine

Known as: F(2)Pmp, F2-Pmp, phosphonodifluoromethylene phenylalanine 
 
National Institutes of Health

Papers overview

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2012
2012
Protein tyrosine phosphatases (PTPs) constitute a large family of signaling enzymes that control the cellular levels of protein… Expand
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Review
2006
Review
2006
  • T. Burke
  • Current topics in medicinal chemistry
  • 2006
  • Corpus ID: 3018383
Hydrolytically-stable phosphotyrosyl (pTyr) mimetics can be useful tools for the study of cellular signal transduction processes… Expand
2005
2005
Phosphotyrosine (pTyr) is an essential component of biological signaling, often being a determinant of protein-protein… Expand
2004
2004
Recent findings have shown that, when expressed in the tripeptide platform, ‘Fmoc‐Glu‐Xxx‐Leu‐amide’, the phosphotyrosyl mimetic… Expand
Highly Cited
2003
Highly Cited
2003
The protein-tyrosine phosphatase SHP-1 plays a variety of roles in the “negative” regulation of cell signaling. The molecular… Expand
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Highly Cited
2003
Highly Cited
2003
The regulation of the protein tyrosine phosphatase (PTPase) SHP-2 by tyrosine phosphorylation has been difficult to elucidate… Expand
2003
2003
The protein-tyrosine phosphatase (PTP) 'YopH' is a virulence factor of Yersinia pestis, the causative agent of plague. Potential… Expand
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2002
2002
Inhibitors of PTP-1B could be therapeutically beneficial in the treatment of type 2 diabetes. Owing to the large number of… Expand
2002
2002
Three peptides, 7-9, bearing sulfono(difluoromethyl)phenylalanine (F(2)Smp, 2), a nonhydrolyzable, monoanionic phosphotyrosine… Expand