phospholipomannan

 
National Institutes of Health

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Glycolipids

Papers overview

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2012
2012
Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on β-mannosylation of the phospholipomannan cell-wall glycosphingolipid.
A family of nine genes encoding proteins involved in the synthesis of β-1,2 mannose adhesins of Candida albicans has been… (More)
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2009
2009
Candida albicans phospholipomannan triggers inflammatory responses of human keratinocytes through Toll-like receptor 2.
The Toll-like receptors (TLRs) play an important role in the recognition of Candida albicans components and activation of innate… (More)
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2008
2008
Identification of a new family of genes involved in beta-1,2-mannosylation of glycans in Pichia pastoris and Candida albicans.
Structural studies of cell wall components of the pathogenic yeast Candida albicans have demonstrated the presence of beta-1,2… (More)
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Highly Cited
2003
Highly Cited
2003
Candida albicans phospholipomannan is sensed through toll-like receptors.
Candida albicans is a common, harmless yeast in the human digestive tract that also causes severe systemic fungal infection in… (More)
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2003
2003
Candida albicans phospholipomannan promotes survival of phagocytosed yeasts through modulation of bad phosphorylation and macrophage apoptosis.
The surface of the pathogenic yeast Candida albicans is coated with phospholipomannan (PLM), a phylogenetically unique glycolipid… (More)
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Review
2003
Review
2003
Role of phospholipomannan in Candida albicans escape from macrophages and induction of cell apoptosis through regulation of bad phosphorylation.
Candida albicans, the most common opportunistic fungal pathogen of humans is a part of the normal microbial flora. To investigate… (More)
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2002
2002
Candida albicans phospholipomannan, a new member of the fungal mannose inositol phosphoceramide family.
The pathogenic yeast Candida albicans has the ability to synthesize unique sequences of beta-1,2-oligomannosides that act as… (More)
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2002
2002
Contribution of phospholipomannan to the surface expression of beta-1,2-oligomannosides in Candida albicans and its presence in cell wall extracts.
beta-1,2-Oligomannosides (beta-1,2-Man) derived from Candida albicans mannan have been shown to act as adhesins and to induce… (More)
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1999
1999
The Candida albicans phospholipomannan is a family of glycolipids presenting phosphoinositolmannosides with long linear chains of beta-1,2-linked mannose residues.
In a series of studies, we have shown that Candida albicans synthesizes a glycolipid, phospholipomannan (PLM), which reacted with… (More)
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1994
1994
The Candida albicans phospholipomannan induces in vitro production of tumour necrosis factor-alpha from human and murine macrophages.
We have previously identified a Candida albicans 14,000-18,000 MW antigen reacting with anti-beta-1,2-linked oligomannosides… (More)
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