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phospholipomannan

 
National Institutes of Health

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Glycolipids

Papers overview

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2012
2012
Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on β-mannosylation of the phospholipomannan cell-wall glycosphingolipid.
A family of nine genes encoding proteins involved in the synthesis of β-1,2 mannose adhesins of Candida albicans has been… Expand
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Highly Cited
2009
Highly Cited
2009
Candida albicans phospholipomannan triggers inflammatory responses of human keratinocytes through Toll‐like receptor 2
Abstract:  The Toll‐like receptors (TLRs) play an important role in the recognition of Candida albicans components and activation… Expand
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2005
2005
Candida albicans serotype B strains synthesize a serotype‐specific phospholipomannan overexpressing a β‐1,2‐linked mannotriose
Candida albicans strains consist of serotypes A and B depending on the presence of terminal β‐1,2‐linked mannose residues in the… Expand
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Review
2004
Review
2004
Toll-like receptors as key mediators in innate antifungal immunity.
The Toll protein of Drosophila is a transmembrane receptor involved in dorsoventral polarization during embryonic development and… Expand
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Highly Cited
2003
Highly Cited
2003
Candida albicans phospholipomannan is sensed through toll-like receptors.
Candida albicans is a common, harmless yeast in the human digestive tract that also causes severe systemic fungal infection in… Expand
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Highly Cited
2003
Highly Cited
2003
Candida albicans Phospholipomannan Promotes Survival of Phagocytosed Yeasts through Modulation of Bad Phosphorylation and Macrophage Apoptosis*
The surface of the pathogenic yeast Candida albicans is coated with phospholipomannan (PLM), a phylogenetically unique glycolipid… Expand
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Highly Cited
2002
Highly Cited
2002
Candida albicans Phospholipomannan, a New Member of the Fungal Mannose Inositol Phosphoceramide Family*
The pathogenic yeast Candida albicanshas the ability to synthesize unique sequences of β-1,2-oligomannosides that act as adhesins… Expand
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2002
2002
Contribution of Phospholipomannan to the Surface Expression of β-1,2-Oligomannosides in Candida albicans and Its Presence in Cell Wall Extracts
ABSTRACT β-1,2-Oligomannosides (β-1,2-Man) derived from Candida albicans mannan have been shown to act as adhesins and to induce… Expand
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1999
1999
The Candida albicans Phospholipomannan Is a Family of Glycolipids Presenting Phosphoinositolmannosides with Long Linear Chains of β-1,2-Linked Mannose Residues*
In a series of studies, we have shown thatCandida albicans synthesizes a glycolipid, phospholipomannan (PLM), which reacted with… Expand
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Highly Cited
1994
Highly Cited
1994
The Candida albicans phospholipomannan induces in vitro production of tumour necrosis factor-alpha from human and murine macrophages.
We have previously identified a Candida albicans 14,000-18,000 MW antigen reacting with anti-beta-1,2-linked oligomannosides… Expand
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