Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on β-mannosylation of the phospholipomannan cell-wall glycosphingolipid.

@article{Mille2012Members5A,
  title={Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on β-mannosylation of the phospholipomannan cell-wall glycosphingolipid.},
  author={C{\'e}line Mille and C. Fradin and Florence Delplace and P A Trinel and Annick Masset and Nadine François and Bernadette Coddeville and Piotr Bobrowicz and Thierry Jouault and Yann Gu{\'e}rardel and Stefan Wildt and Guilhem Janbon and Daniel Poulain},
  journal={Glycobiology},
  year={2012},
  volume={22 10},
  pages={1332-42}
}
A family of nine genes encoding proteins involved in the synthesis of β-1,2 mannose adhesins of Candida albicans has been identified. Four of these genes, BMT1-4, encode enzymes acting stepwise to add β-mannoses on to cell-wall phosphopeptidomannan (PPM). None of these acts on phospholipomannan (PLM), a glycosphingolipid member of the mannose-inositol-phosphoceramide family, which contributes with PPM to β-mannose surface expression. We show that deletion of BMT5 and BMT6 led to a dramatic… CONTINUE READING