phospholipase C1
National Institutes of Health
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Curcumin is naturally occurring polyphenolic compound found in turmeric and has many pharmacological activities. The present…
Phospholipase Cγ1 (PLCγ1) is highly expressed in several tumors. We have previously reported that both stable and inducible PLCγ1…
Mast cell degranulation is a dynamic, highly organized process involving numerous signaling molecules and enzymes. Although the…
One of the key drivers for squamous cell carcinoma (SCC) proliferation is activation of the epidermal growth factor receptor…
OBJECTIVE Regulation of obesity development is an important issue to prevent metabolic syndromes. Gene-disrupted mice of…
Hyperphosphorylation at the Y705 residue of signal transducer and activator of transcription 3 (STAT3) is implicated in…
Aims Lipopolysaccharide (LPS) induces tumor necrosis factor-α (TNF-α) expression in cardiomyocytes, which contributes to…
Phospholipase Cγ1 (PLCγ1) is activated downstream of a variety of extracellular stimuli and has previously been implicated in the…
While it is known that the constitutive activity of a variety of signal transduction molecules leads to cell transformation, a…