phospholipase A2 activity

Known as: lecithinase A activity, phosphatidolipase activity, phosphatidylcholine 2-acylhydrolase activity 
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. [EC:3.1.1.4]

Topic mentions per year

Topic mentions per year

1948-2017
05019482016

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been proposed as an inflammatory marker of cardiovascular… (More)
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Highly Cited
2001
Highly Cited
2001
Inflammation causes the induction of cyclooxygenase-2 (Cox-2), leading to the release of prostanoids, which sensitize peripheral… (More)
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Highly Cited
1999
Highly Cited
1999
Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory mediator with the unique ability to counter… (More)
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1995
1995
Phospholipase A2 (PLA2) is a key-enzyme in the metabolism of membrane phospholipids. In cholinergic neurons PLA2 controls the… (More)
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1995
1995
The intracellular enzyme phospholipase A2 (PLA2) plays an essential role in the breakdown of membrane phospholipids, which… (More)
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1995
1995
Phospholipase A2 activity in human muscle with or without dystrophin abnormality was studied. The results showed an increased… (More)
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Highly Cited
1990
Highly Cited
1990
Inflammation of neural elements is frequently mentioned clinically in association with lumbar radiculopathy. Mechanical… (More)
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1990
1990
Phospholipase A2 (PLA2) is a key enzyme in the metabolism of phospholipids. Because a disordered phospholipid metabolism has… (More)
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1986
1986
Although progesterone is known to produce quiescence in the mammalian uterus, the mechanism of this effect is not clearly… (More)
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Highly Cited
1985
Highly Cited
1985
Previous studies have established that incubation of low density lipoprotein (LDL) with cultured endothelial cells (EC) converts… (More)
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