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phospholipase A2 activity

Known as: lecithinase A activity, phosphatidolipase activity, phosphatidylcholine 2-acylhydrolase activity 
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. [EC:3.1.1.4]
National Institutes of Health

Papers overview

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2016
2016
Peroxiredoxin 6 (Prdx6) is essential for activation of NADPH oxidase type 2 (NOX2) in pulmonary microvascular endothelial cells… Expand
Highly Cited
1993
Highly Cited
1993
Angiotensin II (Ang II) receptors are coupled to a variety of signal transduction mechanisms. In the kidney, Ang II at nanomolar… Expand
1991
1991
Free radical species have been implicated as important agents in ischemia-reperfusion injury associated to transplantation… Expand
Highly Cited
1989
Highly Cited
1989
We have investigated the effects of recombinant interleukin-1 beta (rIL-1 beta) on phospholipase A2 activity (PLA2), PLA2… Expand
1989
1989
Oligomers of prostaglandin B1 inhibited phospholipase A2 extracted from human neutrophils in a dose-dependent manner (IC50 = 5… Expand
Highly Cited
1987
Highly Cited
1987
  • A. Ho, D. Klein
  • The Journal of biological chemistry
  • 1987
  • Corpus ID: 22280598
The regulation of pineal phospholipase A2 activity was studied indirectly by measuring the release of [3H]arachidonic acid from… Expand
Highly Cited
1986
Highly Cited
1986
Leukotriene D4 stimulates prostanoid synthesis in smooth muscle and endothelial cells. Because phospholipases A2 and C have been… Expand
Highly Cited
1982
Highly Cited
1982
Phospholipase A2 activity in islet cell homogenates and dispersed islet cells of the rat was determined using an exogenous… Expand
Highly Cited
1979
Highly Cited
1979
A membrane bound phospholipase A2 (phosphatide 2-acylhydrolase, EC 3.1.1.4) from human platelets has been purified 3500-fold, and… Expand
Highly Cited
1977
Highly Cited
1977
Effect of lipid peroxidation on phospholipase A1 activity was examined in rat liver mitochondria. Content of lipid peroxides in… Expand