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phospholipase A2 activity

Known as: lecithinase A activity, phosphatidolipase activity, phosphatidylcholine 2-acylhydrolase activity 
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. [EC:3.1.1.4]
National Institutes of Health

Related topics

Related topics

4 relations
Phospholipases A2negative regulation of phospholipase A2 activityphospholipase A activity

Narrower (1)

cytosolic phospholipase A2 activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages
Peroxiredoxin 6 (Prdx6) is essential for activation of NADPH oxidase type 2 (NOX2) in pulmonary microvascular endothelial cells… Expand
Highly Cited
1993
Highly Cited
1993
Modulation of phospholipase A2 activity and sodium transport by angiotensin-(1-7).
Angiotensin II (Ang II) receptors are coupled to a variety of signal transduction mechanisms. In the kidney, Ang II at nanomolar… Expand
1991
1991
TISSULAR PROSTANOID RELEASE, PHOSPHOLIPASE A2 ACTIVITY, AND LIPID PEROXIDATION IN PANCREAS TRANSPLANTATION
Free radical species have been implicated as important agents in ischemia-reperfusion injury associated to transplantation… Expand
Highly Cited
1989
Highly Cited
1989
Effects of recombinant interleukin-1 beta on phospholipase A2 activity, phospholipase A2 mRNA levels, and eicosanoid formation in rabbit chondrocytes.
We have investigated the effects of recombinant interleukin-1 beta (rIL-1 beta) on phospholipase A2 activity (PLA2), PLA2… Expand
1989
1989
Oligomers of prostaglandin B1 inhibit in vitro phospholipase A2 activity.
Oligomers of prostaglandin B1 inhibited phospholipase A2 extracted from human neutrophils in a dose-dependent manner (IC50 = 5… Expand
Highly Cited
1987
Highly Cited
1987
Activation of alpha 1-adrenoceptors, protein kinase C, or treatment with intracellular free Ca2+ elevating agents increases pineal phospholipase A2 activity. Evidence that protein kinase C may…
  • A. Ho, D. Klein
  • The Journal of biological chemistry
  • 1987
    • Corpus ID: 22280598
The regulation of pineal phospholipase A2 activity was studied indirectly by measuring the release of [3H]arachidonic acid from… Expand
Highly Cited
1986
Highly Cited
1986
Leukotriene D4 treatment of bovine aortic endothelial cells and murine smooth muscle cells in culture results in an increase in phospholipase A2 activity.
Leukotriene D4 stimulates prostanoid synthesis in smooth muscle and endothelial cells. Because phospholipases A2 and C have been… Expand
Highly Cited
1982
Highly Cited
1982
Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose.
Phospholipase A2 activity in islet cell homogenates and dispersed islet cells of the rat was determined using an exogenous… Expand
Highly Cited
1979
Highly Cited
1979
Modulation of purified phospholipase A2 activity from human platelets by calcium and indomethacin.
A membrane bound phospholipase A2 (phosphatide 2-acylhydrolase, EC 3.1.1.4) from human platelets has been purified 3500-fold, and… Expand
Highly Cited
1977
Highly Cited
1977
Effect of lipid peroxidation on phospholipase A2 activity of rat liver mitochondria.
Effect of lipid peroxidation on phospholipase A1 activity was examined in rat liver mitochondria. Content of lipid peroxides in… Expand
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