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phospholipase A2, group X protein

Known as: Group X Secretory Phospholipase A(2), Phospholipases A2, Group X, sPLA2-X 
A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a… Expand
National Institutes of Health

Papers overview

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2016
2016
Within the secreted phospholipase A2 (sPLA2) family, group X sPLA2 (sPLA2-X) has the highest capacity to hydrolyze cellular… Expand
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2010
2010
Secreted phospholipase A2 group X (sPLA2-X) has recently been identified in the airways of patients with asthma and may… Expand
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Highly Cited
2008
Highly Cited
2008
Secreted phospholipase A2 group X (sPLA2-X) is one of the most potent enzymes of the phospholipase A2 lipolytic enzyme… Expand
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Highly Cited
2008
Highly Cited
2008
Background— Group X secretory phospholipase A2 (sPLA2-X) has the most potent hydrolyzing activity toward phosphatidylcholine and… Expand
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Highly Cited
2007
Highly Cited
2007
RATIONALE Secreted phospholipase A(2) enzymes (sPLA(2)s) play key regulatory roles in the biosynthesis of eicosanoids, such as… Expand
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Highly Cited
2007
Highly Cited
2007
Arachidonic acid metabolites, the eicosanoids, are key mediators of allergen-induced airway inflammation and remodeling in asthma… Expand
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2005
2005
Although group IIA secretory phospholipase A2 (sPLA2-IIA) is known to be abundantly present in the joints of patients with… Expand
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Highly Cited
2002
Highly Cited
2002
The deposition of cholesterol ester within foam cells of the artery wall is fundamental to the pathogenesis of atherosclerosis… Expand
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2000
2000
Group X secretory phospholipase A2 (sPLA2-X) has recently been shown to possess a powerful potency for releasing arachidonic acid… Expand
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Highly Cited
1999
Highly Cited
1999
Group X secretory phospholipase A2 (sPLA2-X) possesses several structural features characteristic of both group IB and IIA sPLA2s… Expand
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