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phospholipase A2, group X protein

Known as: Group X Secretory Phospholipase A(2), Phospholipases A2, Group X, sPLA2-X 
A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a… 
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

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Pla2g10 protein, mouse

Papers overview

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Highly Cited
2008
Highly Cited
2008
Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology*
Secreted phospholipase A2 group X (sPLA2-X) is one of the most potent enzymes of the phospholipase A2 lipolytic enzyme… 
Highly Cited
2006
Highly Cited
2006
Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction*
In an effort to elucidate the functions of secreted phospholipase A2 (sPLA2) enzymes in vivo, we generated transgenic (Tg) mice… 
Highly Cited
2005
Highly Cited
2005
Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells
Although group IIA secretory phospholipase A2 (sPLA2‐IIA) is known to be abundantly present in the joints of patients with… 
Highly Cited
2005
Highly Cited
2005
Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A2*
Although individual mammalian secreted phospholipase A2 (sPLA2) enzymes exhibit unique tissue and cellular distributions, the… 
Highly Cited
2003
Highly Cited
2003
Group V and X secretory phospholipase A(2)s-induced modification of high-density lipoprotein linked to the reduction of its antiatherogenic functions.
Highly Cited
2002
Highly Cited
2002
Potent Modification of Low Density Lipoprotein by Group X Secretory Phospholipase A2 Is Linked to Macrophage Foam Cell Formation*
The deposition of cholesterol ester within foam cells of the artery wall is fundamental to the pathogenesis of atherosclerosis… 
Review
2002
Review
2002
Phospholipase A2 receptor: a regulator of biological functions of secretory phospholipase A2.
Highly Cited
2000
Highly Cited
2000
Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor.
Group X secretory phospholipase A2 (sPLA2-X) has recently been shown to possess a powerful potency for releasing arachidonic acid… 
Review
2000
Review
2000
Cellular components that functionally interact with signaling phospholipase A(2)s.
Highly Cited
1999
Highly Cited
1999
On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
Over the last decade, an expanding diversity of secreted phospholipases A(2) (sPLA(2)s) has been identified in mammals. Here, we… 
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