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phosphofructokinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule. [GOC:jl]
National Institutes of Health

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Related topics

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6-Phosphofructokinase

Papers overview

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Highly Cited
2001
Highly Cited
2001
Twofold reduction of phosphofructokinase activity in Lactococcus lactis results in strong decreases in growth rate and in glycolytic flux.
Two mutant strains of Lactococcus lactis in which the promoter of the las operon, harboring pfk, pyk, and ldh, were replaced by… Expand
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1998
1998
Shared biochemical properties of glucotoxicity and lipotoxicity in islets decrease citrate synthase activity and increase phosphofructokinase activity.
Diabetic states are characterized by a raised serum/islet level of triglycerides and a lowered EC50 (concentration at half… Expand
Highly Cited
1998
Highly Cited
1998
Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets.
The physiological role of nitric oxide (NO) on the mechanism of insulin secretion is unknown, but some studies suggest that NO… Expand
Highly Cited
1994
Highly Cited
1994
Nitric oxide opens ATP-sensitive K+ channels through suppression of phosphofructokinase activity and inhibits glucose-induced insulin release in pancreatic beta cells
Nitric oxide (NO) is known to be a potent messenger in the intracellular signal transduction system in many tissues. In… Expand
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Highly Cited
1981
Highly Cited
1981
Stimulation of yeast phosphofructokinase activity by fructose 2,6-bisphosphate.
  • G. Avigad
  • Biochemical and biophysical research…
  • 1981
    • Corpus ID: 37734699
Abstract Fructose 2,6-bisphosphate is a powerful activator of yeast phosphofructokinase when assayed at pH levels of ≥7.0. Half… Expand
Highly Cited
1979
Highly Cited
1979
Regulation of phosphofructokinase activity by glucagon in isolated rat hepatocytes.
Abstract Glucagon addition to isolated hepatocytes from fed rats resulted in an inhibition of the activity of phosphofructokinase… Expand
Highly Cited
1978
Highly Cited
1978
Glycolysis of quiescent cultures of 3T3 cells. Addition of serum, epidermal growth factor, and insulin increases the activity of phosphofructokinase in a protein synthesis-independent manner.
Addition of serum to quiescent cultures of 3T3 cells markedly enhances the specific activity of phosphofructokinase assayed in… Expand
Highly Cited
1977
Highly Cited
1977
Chloroplast phosphofructokinase: I. Proof of phosphofructokinase activity in chloroplasts.
Ammonium sulfate fractionation of an extract from the leaves of spinach (Spinacia oleracea L.) produced two fractions of… Expand
Highly Cited
1968
Highly Cited
1968
Control of reduced diphosphopyridine nucleotide oscillations in beef heart extracts. I. Effects of modifiers of phosphofructokinase activity.
  • R. Frenkel
  • Archives of biochemistry and biophysics
  • 1968
    • Corpus ID: 30289296
Abstract Beef heart extracts showing cyclic oscillations in the level of reduced diphospho-pyridine nucleotide were studied with… Expand
Highly Cited
1957
Highly Cited
1957
The relationship between inhibition of phosphofructokinase activity and the mode of action of trivalent organic antimonials on Schistosoma mansoni.
The addition of purified mammalian phosphofructokinase to homogenates of schistosoma mansoni increased the rate of lactic acid… Expand
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