Semantic Scholar uses AI to extract papers important to this topic.
Phosphatidylinositol phosphates (PIPs) function as important second messengers in many cellular events. In the human intestinal… Expand Abstract Autophagy is an essential and conserved cellular homeostatic process. Defects in the core and accessory components of… Expand Sorting nexins anchor trafficking machines to membranes by binding phospholipids. The paradigm of the superfamily is sorting… Expand The erlin1/2 complex is a ∼2-MDa endoplasmic reticulum membrane–located ensemble of the ∼40-kDa type II membrane proteins erlin1… Expand Plasmodium falciparum exports proteins into erythrocytes using the Plasmodium export element (PEXEL) motif, which is cleaved in… Expand Recent work has led to the identification of novel endocytic compartments with functional roles in both protein trafficking and… Expand The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in… Expand Dbl family guanine nucleotide exchange factors (GEFs) for Rho family small GTPases invariably contain a pleckstrin homology (PH… Expand Introduction The endocytic pathway plays an important role in regulating the activities of signalling receptors. Experiments that… Expand Activated GTP-bound Rab proteins are thought to interact with effectors to elicit vesicle targeting and fusion events. Vesicle… Expand