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phosphatidylinositol-3-phosphate binding

Known as: PtdIns-3-P binding, phosphatidylinositol 3-phosphate binding 
Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is… 
National Institutes of Health

Papers overview

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2019
2019
Two isotypes of phosphatidylinositol 3‐phosphate‐binding sorting nexins play distinct roles in trogocytosis in Entamoeba histolytica
Phosphatidylinositol phosphates (PIPs) function as important second messengers in many cellular events. In the human intestinal… 
2019
2019
Beta-propeller protein-associated neurodegeneration (BPAN) as a genetically simple model of multifaceted neuropathology resulting from defects in autophagy
Abstract Autophagy is an essential and conserved cellular homeostatic process. Defects in the core and accessory components of… 
2018
2018
Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting
Sorting nexins anchor trafficking machines to membranes by binding phospholipids. The paradigm of the superfamily is sorting… 
2017
2017
Activation of neutrophil respiratory burst by fungal particles requires phosphatidylinositol 3-phosphate binding to p40 phox in humans but not in mice
2015
2015
Lipid Binding Defects and Perturbed Synaptogenic Activity of a Collybistin R290H Mutant That Causes Epilepsy and Intellectual Disability*
Background: A Collybistin R290H mutation causes epilepsy and intellectual disability in humans. Results: Collybistin R290H is… 
Highly Cited
2006
Highly Cited
2006
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in… 
Highly Cited
2003
Highly Cited
2003
Loss of Phosphatidylinositol 3-Phosphate Binding by the C-terminal Tiam-1 Pleckstrin Homology Domain Prevents in Vivo Rac1 Activation without Affecting Membrane Targeting*
Dbl family guanine nucleotide exchange factors (GEFs) for Rho family small GTPases invariably contain a pleckstrin homology (PH… 
2000
2000
Effects of phosphatidylinositol 3-phosphate binding proteins on endosomal dynamics.
1999
1999
Regulation of early-endosome dynamics by phosphatidylinositol 3-phosphate binding proteins.
Introduction The endocytic pathway plays an important role in regulating the activities of signalling receptors. Experiments that… 
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