phorboxazole B

The synthesis of the C1-C19 bis-pyran unit of phorboxazole B has been achieved. The key pyran rings were constructed by means of… Expand

An efficient and highly convergent total synthesis of the potent antitumor agent phorboxazole B has been achieved. The synthetic… Expand

[reaction: see text]. Three segment-coupling Prins approaches to the C3-C19 segment of phorboxazole B have been developed. One… Expand

The convergent syntheses of the C(1-32) and C(33-46) domains of phorboxazole B are described. An iterative cyclocondensation… Expand

An efficient synthesis of the C20-C46 segment of phorboxazole B is described. The key steps involved Hg(OAc)(2)/I(2)-induced… Expand

An efficient synthesis of the C20-C46 segment of phorboxazole B is described. The key steps involved Hg(OAc)(2)/I-2-induced… Expand

The C1-C17 bis-oxane subunit 22 of phorboxazole B is efficiently synthesized by exploiting differential reactivities between… Expand

A steroselective synthesis of C28-C46 segment of phorboxazole B is described. Key features of the synthetic route involved the… Expand

A convergent and enantioselective synthesis of the C13-C19 bis-oxane oxazole fragment of phorboxazole B has been described. This… Expand

The synthesis of phorboxazole B has been accomplished in 27 linear steps and an overall yield of 12.6%. The absolute… Expand