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phorbol-diester hydrolase activity

Known as: phorbol-12,13-diester 12-ester hydrolase activity, 12,13-diacylphorbate 12-acylhydrolase activity, diacylphorbate 12-hydrolase activity 
Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate. [EC:3.1.1.51, RHEA:21319]
National Institutes of Health

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1982
1982
Phorbol-12,13-diester 12-ester hydrolase may prevent tumour promotion by phorbol diesters in skin
Tumour promoters are not themselves carcinogenic but can induce tumours in mice treated previously with an otherwise insufficient… 
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