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peripheral tolerance induction

Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. [GO_REF:0000022, GOC:jal… Expand
National Institutes of Health

Papers overview

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Review
2015
Review
2015
T Cell Motility as Modulator of Interactions with Dendritic Cells
It is well established that the balance of costimulatory and inhibitory signals during interactions with dendritic cells (DCs… Expand
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2008
2008
Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration.
A major problem in generating effective antitumor CTL responses is that most tumors express self-antigens to which the immune… Expand
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2007
2007
Programmed cell death 1 (PD-1) and its ligand PD-L1 are required for allograft tolerance.
Programmed cell death-1 (PD-1, CD279) and its widely expressed, inducible ligand, PD-L1 (CD274), together dampen T cell… Expand
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Review
2006
Review
2006
CD4+CD25+ regulatory T cells and graft-versus-host disease.
Peripheral suppression of autoreactive T cells by specialized T-cell populations is one of several mechanisms ensuring self… Expand
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2006
2006
Direct versus indirect allorecognition: Visualization of dendritic cell distribution and interactions during rejection and tolerization.
Interactions of donor and recipient dendritic cells (DCs) with CD4+ T cells determine the alloantigenic response in organ… Expand
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Review
2005
Review
2005
Immunomodulation after allogeneic bone marrow transplantation by CD4+CD25+ regulatory T cells.
Graft-versus-host disease is a major complication after allogeneic bone marrow transplantation (BMT) caused by donor T cells… Expand
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2002
2002
CD40 ligation in the presence of self-reactive CD8 T cells leads to severe immunopathology.
Previous work has shown that stimulation of APCs via CD40 strongly influences the outcome of a CD8 T cell response. In this study… Expand
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Highly Cited
2001
Highly Cited
2001
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen.
Immunoregulatory CD25(+)CD4 T cells are thought to arise from the thymus as a distinct lineage of CD4 T cells specific for self… Expand
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