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perillic acid

Known as: 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid, 4-Isopropenylcyclohex-1-enecarboxylic Acid, 4-(2-propenyl)-1-cyclohexane-1-carboxylic acid 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CyclohexenesMonoterpenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
OBTENCIÓN DE ALCOHOL PERÍLICO POR BIOTRANSFORMACIÓN DEL LIMONENO
Limonene is the most abundant cyclic monoterpene in nature. R-(+)-limonene is the main compound of citrus fruits flavedo (orange… 
2005
2005
The apoptosis-inducing activity of natural plant products involved regulation of events downstream of the p53 pathway
5902 Natural plant products such as perillyl alcohol and their metabolites have been reported to possess anti-tumor and drug… 
2003
2003
Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells
In THP-1 cells, simvastatin decreases, in a concentration-dependent manner, cholesterol synthesis and increases linoleic acid (LA… 
Highly Cited
2002
Highly Cited
2002
Fluvastatin Induces Apoptosis in Rat Neonatal Cardiac Myocytes: A Possible Mechanism of Statin-Attenuated Cardiac Hypertrophy
Hydroxymethylglutaryl CoA (HMG-CoA) reductase inhibitors (statins) have been shown to reduce atherosclerotic cardiovascular… 
Highly Cited
1999
Highly Cited
1999
Blocking signaling through the gp130 receptor chain by interleukin‐6 and oncostatin M inhibits PC‐3 cell growth and sensitizes the tumor cells to etoposide and cisplatin‐mediated cytotoxicity
The mechanisms of drug resistance associated with advanced, hormone‐independent prostate carcinoma are poorly understood. The… 
1997
1997
Analysis of perillic acid in plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
Highly Cited
1996
Highly Cited
1996
Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometry.
Limonene is a farnesyl transferase inhibitor that has shown antitumor properties. The drug had been given orally to cancer… 
Highly Cited
1995
Highly Cited
1995
Isoprenylation of proteins in the protozoan Giardia lamblia.
1993
1993
Multiple signal transduction pathways mediate c-Jun protein phosphorylation.
A variety of protein kinases, including pp42 and pp54 mitogen-activated protein (MAP) kinases, p34cdc2, and a partially purified… 
1949
1949
Structure of Thujic Acid (‘Dehydroperillic Acid’)
‘DEHYDROPERILLIC acid’ (C10H12O2) is an optically inactive acid which has been isolated from the heartwood of western red cedar… 
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