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perillic acid

Known as: 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid, 4-Isopropenylcyclohex-1-enecarboxylic Acid, 4-(2-propenyl)-1-cyclohexane-1-carboxylic acid 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CyclohexenesMonoterpenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
Plant products such as perillyl alcohol have been reported to possess anti-tumor activities against a number of human cancers… Expand
2003
2003
Effect of naturally occurring monoterpenes carvone, limonene and perillic acid in the inhibition of experimental lung metastasis induced by B16F-10 melanoma cells.
The effects of naturally occurring monoterpenes on lung metastasis induced by B16F-10 melanoma cells were studied in C57BL/6 mice… Expand
Highly Cited
2003
Highly Cited
2003
Immunomodulatory Activity of Naturally Occurring Monoterpenes Carvone, Limonene, and Perillic Acid
The immunomodulatory activity of some naturally occurring monoterpenes were studied in Balb/c mice. Administration of various… Expand
Review
2003
Review
2003
Biotransformation of limonene by bacteria, fungi, yeasts, and plants
The past 5 years have seen significant progress in the field of limonene biotransformation, especially with regard to the… Expand
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2001
2001
Bioconversion of limonene to increased concentrations of perillic acid by Pseudomonas putida GS1 in a fed-batch reactor
Abstract. Pseudomonas putida GS1 is able to convert limonene to perillic acid (up to 64 mM,(11 g/l) when the bacteria is… Expand
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Highly Cited
1999
Highly Cited
1999
Blocking signaling through the gp130 receptor chain by interleukin‐6 and oncostatin M inhibits PC‐3 cell growth and sensitizes the tumor cells to etoposide and cisplatin‐mediated cytotoxicity
The mechanisms of drug resistance associated with advanced, hormone‐independent prostate carcinoma are poorly understood. The… Expand
Highly Cited
1998
Highly Cited
1998
3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture.
Recent evidence suggests that apoptosis may be involved in the control of vascular smooth muscle cell (VSMC) number in… Expand
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Highly Cited
1998
Highly Cited
1998
Phase I and pharmacokinetic study of d-limonene in patients with advanced cancer
Purpose: d-Limonene is a natural monoterpene with pronounced chemotherapeutic activity and minimal toxicity in preclinical… Expand
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1997
1997
Perillic acid inhibits Ras/MAP kinase-driven IL-2 production in human T lymphocytes.
Perillic acid, a major metabolite of d-limonene, substantially suppressed interleukin-2 (IL-2) and IL-10 production in mitogen… Expand
Highly Cited
1991
Highly Cited
1991
Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites.
Limonene has chemotherapeutic activity against chemically induced rat mammary carcinomas, many of which contain activated ras… Expand
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