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pentopril
Known as:
1-(4-(ethoxycarbonyl)-2-methylpentanoyl)-2,3-dihydroindole-2-carboxylic acid
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, pentopril is hydrolyzed into its active…
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National Institutes of Health
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CGS 13945
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1987
1987
Direct determination of angiotensin-converting enzyme inhibitors in plasma by radioenzymatic assay.
P. Reydel-Bax
,
E. Redalieu
,
A. Rakhit
Clinical Chemistry
1987
Corpus ID: 6101392
We describe a simple, rapid, specific radioenzymatic assay for "CGS 16617," a new, potent inhibitor of angiotensin-converting…
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1985
1985
Disposition of pentopril, a new orally active angiotensin-converting enzyme inhibitor, and its active metabolite in rats.
A. Rakhit
,
G. Kochak
,
R. Dotson
,
V. Tipnis
Journal of Pharmacy and Science
1985
Corpus ID: 35567944
The disposition characteristics of pentopril (the ethyl ester) and its active carboxylic acid metabolite (CGS 13934) were…
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1985
1985
Effect of food on the bioavailability of pentopril, an angiotensin-converting-enzyme inhibitor, in healthy subjects.
A. Rakhit
,
M. Hurley
,
+4 authors
A. Rommel
Journal of clinical pharmacology
1985
Corpus ID: 6612096
Pentopril (CGS 13945) was administered in 125-mg capsules to eight healthy men on two occasions according to a randomized…
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