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pentopril

Known as: 1-(4-(ethoxycarbonyl)-2-methylpentanoyl)-2,3-dihydroindole-2-carboxylic acid 
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, pentopril is hydrolyzed into its active… 
National Institutes of Health

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CGS 13945

Papers overview

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2017
2017
Enantioselective Synthesis of trans‐2,3‐Dihydro‐1H‐indoles Through C–H Insertion of α‐Diazocarbonyl Compounds
A stereoselective synthesis of 2,3-dihydro-1H-indoles with a RhII-catalyzed C–H insertion is reported. The α-diazo carbonyl… 
2004
2004
On-line assay of the S-enantiomers of enalapril, ramipril and pentopril using a sequential injection analysis/amperometric biosensor system.
1999
1999
Biosensor for enantioselective analysis of S-cilazapril, S-trandolapril, and S-pentopril.
The purpose of this research was to construct an amperometric biosensor on L-amino acid oxidase (L-AAOD) supported on a carbon… 
1988
1988
Effect of renal impairment on disposition of pentopril and its active metabolite
Disposition of pentopril was studied in 15 male volunteers with varying renal functions. Mild to moderate compromise in renal… 
1987
1987
Pharmacokinetics of pentopril in the elderly.
1 The pharmacokinetics of pentopril in elderly subjects aged 70 to 75 years were compared with those of healthy young subjects… 
1987
1987
Direct determination of angiotensin-converting enzyme inhibitors in plasma by radioenzymatic assay.
We describe a simple, rapid, specific radioenzymatic assay for "CGS 16617," a new, potent inhibitor of angiotensin-converting… 
1985
1985
Effects of Food on the Bioavailability of CGS 16617, an Angiotensin‐Converting Enzyme Inhibitor, in Healthy Subjects
CGS 16617, a direct‐acting angiotensin‐converting‐enzyme inhibitor, was administered as a single dose of 20 mg in aqueous… 
1985
1985
Disposition of pentopril, a new orally active angiotensin-converting enzyme inhibitor, and its active metabolite in rats.
The disposition characteristics of pentopril (the ethyl ester) and its active carboxylic acid metabolite (CGS 13934) were… 
1985
1985
Determination of pentopril, an angiotensin converting enzyme inhibitor, and its active metabolite in urine.
1985
1985
Effect of food on the bioavailability of pentopril, an angiotensin-converting-enzyme inhibitor, in healthy subjects.
Pentopril (CGS 13945) was administered in 125-mg capsules to eight healthy men on two occasions according to a randomized… 
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