pegaptanib

Known as: pegaptanib [Chemical/Ingredient] 
A 28-mer RNA aptamer covalently linked to two branched 20-kD polyethylene glycol (PEG) chains, with anti-angiogenic activity. Pegaptanib binds and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
AIMS To determine the level of vascular endothelial growth factor (VEGF) in the plasma of patients with diabetic macular edema… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Vascular endothelial growth factor (VEGF) antagonists are the therapy of choice for age-related macular degeneration… (More)
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Review
2008
Review
2008
Vascular endothelial growth factor (VEGF) plays a key role in the development of both proliferative diabetic retinopathy (PDR… (More)
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Review
2006
Review
2006
Age-related macular degeneration (AMD) is a major cause of severe visual loss worldwide. Neovascular (wet) AMD accounts for 90… (More)
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Highly Cited
2005
Highly Cited
2005
To determine whether intravitreal bevacizumab could improve optical coherence tomography and visual acuity outcomes in a patient… (More)
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2005
2005
eases are characterised by neovascularisation and Pegaptanib in Exudative Agevascular leakage. VEGF levels have been shown to… (More)
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Review
2005
Review
2005
Age-related macular degeneration is the leading cause of irreversible visual loss in the industrialised world. Angiogenesis… (More)
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2004
2004
BACKGROUND Pegaptanib, an anti-vascular endothelial growth factor therapy, was evaluated in the treatment of neovascular age… (More)
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2003
2003
Eyetech Pharmaceuticals and Pfizer are co-developing the anti-vascular endothelial growth factor aptamer, pegaptanib, as an… (More)
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