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Pegaptanib Sodium

Known as: Pegaptanib Octasodium 
The sodium salt form of pegaptanib, a 28-mer RNA aptamer covalently linked to two branched 20-kD polyethylene glycol (PEG) chains, with anti… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
PURPOSE To confirm the safety and compare the efficacy of intravitreal pegaptanib sodium 0.3 mg versus sham injections in… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To examine associations between therapies for age-related macular degeneration and risks of all-cause mortality… Expand
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Highly Cited
2007
Highly Cited
2007
BackgroundVascular endothelial growth factor (VEGF) plays an important role in many diseases of the posterior pole that are… Expand
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2007
2007
PurposeThe purpose was to report a case of elevated intraocular vascular endothelial growth factor (VEGF) levels in a 2-year-old… Expand
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Review
2006
Review
2006
Aptamers are oligonucleotide ligands that are selected for high-affinity binding to molecular targets. Pegaptanib sodium (Macugen… Expand
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Review
2006
Review
2006
Neovascular age-related macular degeneration (AMD) is a visually devastating condition resulting from choroidal… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To evaluate the efficacy of a second year of pegaptanib sodium therapy in patients with neovascular age-related macular… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To evaluate the safety of pegaptanib sodium injection, a specific vascular endothelial growth factor (VEGF) antagonist… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To study effects of intravitreal pegaptanib (Macugen) on retinal neovascularization. DESIGN Retrospective analysis of… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the safety and efficacy of pegaptanib sodium injection (pegaptanib) in the treatment of diabetic macular… Expand
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