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paxillin

Known as: PXN, Paxillin [Chemical/Ingredient] 
Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response… 
National Institutes of Health

Related topics

Related topics

28 relations
Adaptor Proteins, Signal TransducingAdaptor Signaling Protein GeneAgrin PathwayAngiogenesis Pathway

Broader (2)

CalmodulinCell Adhesion Molecules

Papers overview

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2010
2010
Phosphorylation of paxillin at threonine 538 by PKCδ regulates LFA1-mediated adhesion of lymphoid cells
We investigated the PKCδ-mediated phosphorylation of paxillin within its LIM4 domain and the involvement of this phosphorylation… 
2008
2008
Phosphorylation of paxillin LD4 destabilizes helix formation and inhibits binding to focal adhesion kinase.
Cell migration is a dynamic process that requires the coordinated formation and disassembly of focal adhesions (FAs). Several… 
2006
2006
Dominant‐negative Rac increases both inherent and ionizing radiation‐induced cell migration in C6 rat glioma cells
Rho‐like GTPases, including Cdc42, Rac1 and RhoA, regulate distinct actin cytoskeleton changes required for cell adhesion… 
2004
2004
Differential Regulation of Focal Adhesion Kinase and Paxillin Phosphorylation by the Small GTP-binding Protein Rho in Human Corneal Epithelial Cells
PurposeLysophosphatidic acid (LPA), which activates the small guanosine triphosphate (GTP)-binding protein Rho, was previously… 
2003
2003
Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells
Tyrosine phosphorylation of the nonreceptor tyrosine kinase p125 focal adhesion kinase (FAK) and the adapter protein paxillin is… 
2001
2001
Differential phosphorylation of paxillin in response to surface-bound serum proteins during early osteoblast adhesion.
An early signaling event during the adhesion and spreading of cells is integrin-mediated tyrosine phosphorylation of the… 
1999
1999
Characterization of paxillin LIM domain‐associated serine threonine kinases: Activation by angiotensin II in vascular smooth muscle cells
Recently we reported a novel means of regulating LIM domain protein function. Paxillin LIM zinc‐finger phosphorylation in… 
1998
1998
Tyrosine phosphorylation of paxillin/pp125FAK and microvascular endothelial barrier function.
The transendothelial movement of solutes is a dynamic process controlled by a complex interaction between the cytoskeleton and… 
1997
1997
Endothelial nitric oxide synthase gene transfer inhibits platelet-derived growth factor-BB stimulated focal adhesion kinase and paxillin phosphorylation in vascular smooth muscle cells.
Stimulation of smooth muscle (VSM) cells of guinea pig coronary artery by platelet-derived growth factor (PDGF)-BB retards… 
1971
1971
Étude du mécanisme des réactions nucléaires induites par particules alpha de haute énergie II. Réactions 208Pb(α, xn) 212-xPo et 208 206Pb(α, pxn) Bi. noyau composé et mécanismes non composés
2014 This second paper dealing with the study of 4He induced reactions on heavy nuclei (see reference [1]) gives the experimental… 
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