paxillin

Known as: PXN, Paxillin [Chemical/Ingredient] 
Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Focal adhesions (FAs) are mechanosensitive adhesion and signaling complexes that grow and change composition in response to… (More)
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Highly Cited
2007
Highly Cited
2007
Diverse cellular processes are carried out by distinct integrin-mediated adhesions. Cell spreading and migration are driven by… (More)
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Highly Cited
2006
Highly Cited
2006
Continuous adhesion formation and disassembly (adhesion turnover) in the protrusions of migrating cells is regulated by unclear… (More)
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Highly Cited
1999
Highly Cited
1999
Paxillin is a focal adhesion adaptor protein involved in the integration of growth factor- and adhesion-mediated signal… (More)
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Highly Cited
1997
Highly Cited
1997
pp125FAK is a tyrosine kinase that appears to regulate the assembly of focal adhesions and thereby promotes cell spreading on the… (More)
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Highly Cited
1996
Highly Cited
1996
Paxillin is a 68-kD focal adhesion phosphoprotein that interacts with several proteins including members of the src family of… (More)
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Highly Cited
1995
Highly Cited
1995
Paxillin, a focal-adhesion-associated protein, becomes phosphorylated in response to a number of stimuli which also induce the… (More)
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Highly Cited
1995
Highly Cited
1995
The concomitant tyrosine phosphorylation of the focal adhesion protein, paxillin, and the tyrosine kinase, focal adhesion kinase… (More)
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Highly Cited
1994
Highly Cited
1994
Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix… (More)
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Highly Cited
1992
Highly Cited
1992
Cells in culture reveal high levels of protein tyrosine phosphorylation in their focal adhesions, the regions where cells adhere… (More)
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