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paraspeckles

Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically… 
National Institutes of Health

Papers overview

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2019
2019
Dynamic paraspeckle component localization during spermatogenesis.
Expression profiles and subcellular localisations of core Drosophila behaviour/human splicing (DBHS) proteins (PSPC1, SFPQ and… 
2017
2017
Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation
Altered expression of NEAT1, the architectural long non-coding RNA (lncRNA) of nuclear paraspeckles, has been reported during… 
2017
2017
Paraspeckles: nuclear nests helping to raise mature miRNAs
  • J. Krol
  • Nature Structural &Molecular Biology
  • 2017
  • Corpus ID: 39928640
The cellular crosstalk between different classes of regulatory noncoding RNAs has reached a new spatial dimension. Jiang et al… 
Review
2017
Review
2017
Paraspeckles as rhythmic nuclear mRNA anchorages responsible for circadian gene expression
ABSTRACT Circadian clocks regulate rhythmic gene expression levels by means of mRNA oscillations that are mainly driven by post… 
2016
2016
Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic Catastrophe
Previously, we have shown that paraspeckle protein 1 (PSPC1), a protein component of paraspeckles that was involved in cisplatin… 
2015
2015
Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles
Paraspeckle protein 1 (PSPC1), a component of nuclear paraspeckles, is identified as an importin α2 (IMPα2) binding partner in… 
Review
2014
Review
2014
Long non-coding RNAs learn the importance of being in vivo
In the past few years, the long non-coding RNA (lncRNA) field has been dealt some major surprises. While some phenotypes of mice… 
Review
2012
Review
2012
Architectural roles of long noncoding RNAs in the intranuclear formation of functional paraspeckles.
The eukaryotic nucleus is highly compartmentalized, and this structural complexity allows the regulation of complex gene… 
2011
2011
The mitotic phosphorylation of p54(nrb) modulates its RNA binding activity.
The RNA-binding protein p54(nrb) is involved in many nuclear processes including transcription, RNA processing, and retention of… 
Review
2009
Review
2009
How to build a paraspeckle
Noncoding RNAs have recently been identified as essential components of the nuclear suborganelles called paraspeckles. This… 
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