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palmitoyltransferase activity

Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2017
0246819702017

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2009
2009
An improved method to determine serine palmitoyltransferase activity.
Serine palmitoyltransferase (SPT) catalyzes the condensation of l-serine and palmitoyl-CoA, which is the rate-limiting step in… (More)
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Highly Cited
2008
Highly Cited
2008
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity.
CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the brain. The enzyme has recently been… (More)
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2002
2002
Mutations in the yeast LCB1 and LCB2 genes, including those corresponding to the hereditary sensory neuropathy type I mutations, dominantly inactivate serine palmitoyltransferase.
It was recently demonstrated that mutations in the human SPTLC1 gene, encoding the Lcb1p subunit of serine palmitoyltransferase… (More)
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Highly Cited
1997
Highly Cited
1997
Effect of conjugated linoleic acid on body composition in mice
The effects of conjugated linoleic acid (CLA) on body composition were investigated. ICR mice were fed a control diet containing… (More)
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1997
1997
cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons.
The effect of six different structurally modified sphingosine analogues on biosynthesis of sphingolipids was studied in primary… (More)
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1996
1996
G-protein palmitoyltransferase activity is enriched in plasma membranes.
Heterotrimeric G proteins are covalently modified by lipids. Myristoylation of G-protein alpha subunits and prenylation of gamma… (More)
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1994
1994
Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase…
Suppressor mutations in Saccharomyces cerevisiae that block Ca(2+)-induced death of csg2 mutant cells were investigated. These… (More)
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Highly Cited
1993
Highly Cited
1993
Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.
The effect of docosahexaenoic acid (DHA) on mitochondrial and peroxisomal fatty acid oxidation and on key enzymes in triglyceride… (More)
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1987
1987
Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.
The overt carnitine palmitoyltransferase (palmitoyl-CoA:L-carnitine O-palmitoyltransferase, EC 2.3.1.21) activity of intact… (More)
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1983
1983
Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells.
Serine palmitoyltransferase (palmitoyl-CoA: L-serine C-palmitoyltransferase (decarboxylating) EC 2.3.1.50) catalyzes the first… (More)
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