oxybutynin

Known as: Oxybutyninum, 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate 
A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting… (More)
National Institutes of Health

Related topics

Related topics

29 relations
24 HR Oxybutynin chloride 10 MG Extended Release Oral Tablet84 HR oxybutynin 0.162 MG/HR Transdermal System [Oxytrol]Drug AllergyGlaucoma
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Narrower (10)

DitropanOxybutin HolstenOxybutonOxybutynin chloride
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Broader (4)

Mandelic AcidsMuscarinic AntagonistsParasympatholyticsUrological Agents

Papers overview

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Highly Cited
2012
Highly Cited
2012
Persistence with prescribed antimuscarinic therapy for overactive bladder: a UK experience.
UNLABELLED Study Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add… (More)
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Highly Cited
2006
Highly Cited
2006
Differential effects of the antimuscarinic agents darifenacin and oxybutynin ER on memory in older subjects.
OBJECTIVES To investigate the effects of darifenacin controlled-release (CR) and oxybutynin extended-release (ER) on cognitive… (More)
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Highly Cited
2003
Highly Cited
2003
Comparative efficacy and safety of transdermal oxybutynin and oral tolterodine versus placebo in previously treated patients with urge and mixed urinary incontinence.
OBJECTIVES To compare the efficacy and safety of an oxybutynin transdermal delivery system (OXY-TDS) and oral, long-acting… (More)
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Highly Cited
2001
Highly Cited
2001
A short-term, multicenter, randomized double-blind dose titration study of the efficacy and anticholinergic side effects of transdermal compared to immediate release oral oxybutynin treatment of…
PURPOSE We compared the short-term efficacy, safety and tolerability of transdermal versus oral oxybutynin in adults with urge… (More)
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Highly Cited
2001
Highly Cited
2001
Tolterodine: superior tolerability than and comparable efficacy to oxybutynin in individuals 50 years old or older with overactive bladder: a randomized controlled trial.
PURPOSE We compared the tolerability and clinical efficacy of tolterodine with those of oxybutynin in patients with an overactive… (More)
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Review
2001
Review
2001
Oxybutynin and the overactive bladder
 Oxybutynin is a tertiary amine, which undergoes an extensive first-pass metabolism. It has an active metabolite, N-desethyl… (More)
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Highly Cited
1998
Highly Cited
1998
Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder.
OBJECTIVE To compare the efficacy and tolerability of tolterodine with that of oxybutynin in patients with an overactive bladder… (More)
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1995
1995
Oxybutynin with bladder retraining for detrusor instability in elderly people: a randomized controlled trial.
The aim of this study was to examine the efficacy of oxybutynin plus bladder training in the treatment of detrusor instability in… (More)
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1994
1994
Influences of trospium chloride and oxybutynin on quantitative EEG in healthy volunteers
Trospium chloride and oxybutynin are two antimuscarinergic agents used in the treatment of unstable bladder, urge incontinence… (More)
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1988
1988
The pharmacokinetics of oxybutynin in man
We have studied the pharmacokinetics of oxybutynin (Ditropan) after single oral (5 mg) and intravenous administration (1 and 5 mg… (More)
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