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oxybutynin
Known as:
Oxybutyninum
, 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate
, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
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A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting…
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National Institutes of Health
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Related topics
Related topics
32 relations
24 HR Oxybutynin chloride 10 MG Extended Release Oral Tablet
84 HR oxybutynin 0.162 MG/HR Transdermal System [Oxytrol]
Drug Allergy
Glaucoma
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Narrower (13)
Ditropan
Driptane
Oxyb AbZ
Oxybutin Holsten
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Broader (4)
Mandelic Acids
Muscarinic Antagonists
Parasympatholytics
Urological Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder
S. Yamada
,
Yoshihiko Ito
,
S. Nishijima
,
K. Kadekawa
,
K. Sugaya
Pharmacology & therapeutics
2018
Corpus ID: 13979388
ABSTRACT Antimuscarinic agents are now widely used as the pharmacological therapy for overactive bladder (OAB) because neuronal…
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Highly Cited
2012
Highly Cited
2012
Persistence with prescribed antimuscarinic therapy for overactive bladder: a UK experience
A. Wagg
,
G. Compion
,
A. Fahey
,
E. Siddiqui
BJU international
2012
Corpus ID: 26438311
Study Type – Therapy (prevalence)
Highly Cited
2010
Highly Cited
2010
Investigation of the mechanism of C(sp3)-H bond cleavage in Pd(0)-catalyzed intramolecular alkane arylation adjacent to amides and sulfonamides.
S. Rousseaux
,
S. Gorelsky
,
Benjamin K. W. Chung
,
K. Fagnou
Journal of the American Chemical Society
2010
Corpus ID: 5297900
The reactivity of C(sp(3))-H bonds adjacent to a nitrogen atom can be tuned to allow intramolecular alkane arylation under Pd(0…
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Highly Cited
2006
Highly Cited
2006
Differential effects of the antimuscarinic agents darifenacin and oxybutynin ER on memory in older subjects.
G. Kay
,
T. Crook
,
+4 authors
M. Steel
European urology
2006
Corpus ID: 827597
OBJECTIVES To investigate the effects of darifenacin controlled-release (CR) and oxybutynin extended-release (ER) on cognitive…
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Highly Cited
2003
Highly Cited
2003
Comparative efficacy and safety of transdermal oxybutynin and oral tolterodine versus placebo in previously treated patients with urge and mixed urinary incontinence.
R. Dmochowski
,
P. Sand
,
N. Zinner
,
M. Gittelman
,
G. Davila
,
S. Sanders
Urology
2003
Corpus ID: 23005393
OBJECTIVES To compare the efficacy and safety of an oxybutynin transdermal delivery system (OXY-TDS) and oral, long-acting…
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Highly Cited
2001
Highly Cited
2001
Effects of Tolterodine, Trospium Chloride, and Oxybutynin on the Central Nervous System
A. Todorova
,
B. Vonderheid-Guth
,
W. Dimpfel
Journal of clinical pharmacology
2001
Corpus ID: 23465855
Antimuscarinic compounds are increasingly used to treat the symptoms of overactive bladder; however, their use is often…
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Highly Cited
1999
Highly Cited
1999
Clinical Efficacy and Safety of Tolterodine Compared to Oxybutynin and Placebo in Patients with Overactive Bladder
H. Drutz
,
R. Appell
,
D. Gleason
,
I. Klimberg
,
S. Radomski
International Urogynecology Journal
1999
Corpus ID: 22124329
Abstract: This study compared the clinical efficacy (determined from micturition diaries) and safety of 12 weeks’ treatment with…
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Highly Cited
1998
Highly Cited
1998
Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder
Abrams
,
Freeman
,
AnderstrÖM
,
Mattiasson
1998
Corpus ID: 72243415
Objective To compare the efficacy and tolerability of tolterodine with that of oxybutynin in patients with an overactive…
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Highly Cited
1995
Highly Cited
1995
Xerostomia, Xerogenic Medications and Food Avoidances in Selected Geriatric Groups
W. Loesche
,
J. Bromberg
,
+4 authors
S. Langmore
Journal of the American Geriatrics Society
1995
Corpus ID: 17003545
OBJECTIVE: To study the relationship between complaints of xerostomia and salivary performance and food avoidances in four…
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Highly Cited
1991
Highly Cited
1991
Randomized, double-blind, multicenter trial on treatment of frequency, urgency and incontinence related to detrusor hyperactivity: oxybutynin versus propantheline versus placebo.
J. Thueroff
,
B. Bunke
,
+7 authors
W. Schaefer
The Journal of urology
1991
Corpus ID: 23568640
Clinical efficacy and adverse effects of oxybutynin and propantheline in the treatment of symptoms related to detrusor…
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