oxybutynin

Known as: Oxybutyninum, 4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate 
A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
UNLABELLED Study Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES To investigate the effects of darifenacin controlled-release (CR) and oxybutynin extended-release (ER) on cognitive… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES To compare the efficacy and safety of an oxybutynin transdermal delivery system (OXY-TDS) and oral, long-acting… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE We compared the short-term efficacy, safety and tolerability of transdermal versus oral oxybutynin in adults with urge… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE We compared the tolerability and clinical efficacy of tolterodine with those of oxybutynin in patients with an overactive… (More)
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Review
2001
Review
2001
 Oxybutynin is a tertiary amine, which undergoes an extensive first-pass metabolism. It has an active metabolite, N-desethyl… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To compare the efficacy and tolerability of tolterodine with that of oxybutynin in patients with an overactive bladder… (More)
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1995
1995
The aim of this study was to examine the efficacy of oxybutynin plus bladder training in the treatment of detrusor instability in… (More)
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1994
1994
Trospium chloride and oxybutynin are two antimuscarinergic agents used in the treatment of unstable bladder, urge incontinence… (More)
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1988
1988
We have studied the pharmacokinetics of oxybutynin (Ditropan) after single oral (5 mg) and intravenous administration (1 and 5 mg… (More)
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