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ouabagenin

Known as: 1 beta,3 beta,5,11 alpha,14,19- hexahydroxy-5 beta-card-20(22)-enolide, g-strophanthidin 
National Institutes of Health

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2 relations

Broader (1)

Ouabain
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation.
A Cu(II)-catalyzed diastereoselective Michael/aldol cascade approach is used to accomplish concise total syntheses of cardiotonic… 
Highly Cited
2015
Highly Cited
2015
Development of a Concise Synthesis of Ouabagenin and Hydroxylated Corticosteroid Analogues
The natural product ouabagenin is a complex cardiotonic steroid with a highly oxygenated skeleton. This full account describes… 
2009
2009
Total synthesis of ouabagenin and ouabain.
A full account of the total synthesis of ouabagenin and ouabain is described. A highly stereocontrolled anionic cycloaddition for… 
2000
2000
Selective inhibition of human erythrocyte Na+/K+ ATPase by cardiac glycosides and by a mammalian digitalis like factor.
Highly Cited
1994
Highly Cited
1994
Ouabain is not detectable in human plasma.
An enzyme-linked immunosorbent assay is described for the measurement of ouabain in human plasma. This assay is specific for… 
Highly Cited
1993
Highly Cited
1993
Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamus.
Recent reports have shown the presence of a ouabain-like inhibitor of Na+/K(+)-ATPase in humans. We have purified a bovine… 
1986
1986
Identification of an essential sulfhydryl group in the ouabain binding site of (Na,K)-ATPase.
1986
1986
Involvement of (Na+ + K+)-ATPase in binding and actions of palytoxin on human erythrocytes.
Highly Cited
1980
Highly Cited
1980
A kinetic comparison of cardiac glycoside interactions with Na+,K+-ATPases from skeletal and cardiac muscle and from kidney.
Highly Cited
1974
Highly Cited
1974
The nature of the transport adenosine triphosphatase-digitalis complex. VII. Characteristics of ouabagenin-Na+,K+-adenosine triphosphatase interaction.
The inhibitory characteristics of ouabagenin on beef brain and rat heart Na + , K + -adenosine triphosphatase (ATPase… 
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