ototoxicity

Damage to the inner ear as a result of exposure to drugs or chemicals.
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND Intravenous aminoglycoside (IV AG) antibiotics, widely used in patients with cystic fibrosis (CF), are known to have… (More)
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2015
2015
OBJECTIVE Hearing loss is a major side effect of cisplatin chemotherapy. Although cell death in cisplatin-induced ototoxicity is… (More)
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2015
2015
Manganese superoxide dismutase (MnSOD), encoded by the SOD2 gene, is involved in the detoxification of superoxide anion… (More)
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2014
2014
OBJECTIVES/HYPOTHESIS Our objectives were to study effects of orally administered resveratrol (RV) against cisplatin (CDDP… (More)
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2014
2014
OBJECTIVES Silymarin is a plant extract with strong antioxidant properties in addition to anti-inflammatory and anticarcinogenic… (More)
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2014
2014
Paclitaxel (taxol) is a widely used antineoplastic drug employed alone or in combination to treat many forms of cancer… (More)
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2012
2012
Aminoglycosides, such as gentamycin, are well known ototoxic agents. Toxicity occurs via an activation process involving the… (More)
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2011
2011
OBJECTIVE To determine whether intratympanic administration of dexamethasone reduces ototoxicity from systemic cisplatin. STUDY… (More)
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2011
2011
Otolaryngology, although considered a surgical specialty, also covers many diseases that are not cured by surgery. These are… (More)
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Highly Cited
2004
Highly Cited
2004
Cisplatin (CDDP) is a highly effective chemotherapeutic agent but with significant ototoxic side effects. Apoptosis is an… (More)
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