• Publications
  • Influence
Neomycin-Induced Hair Cell Death and Rapid Regeneration in the Lateral Line of Zebrafish (Danio rerio)
Mechanoreceptive hair cells are extremely sensitive to aminoglycoside antibiotics, including neomycin. Hair cell survival was assessed in larval wild-type zebrafish lateral line neuromasts 4 h afterExpand
  • 364
  • 50
  • PDF
Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti.
Hearing loss is most often the result of hair-cell degeneration due to genetic abnormalities or ototoxic and traumatic insults. In the postembryonic and adult mammalian auditory sensory epithelium,Expand
  • 360
  • 29
  • PDF
Notch Signaling Regulates the Extent of Hair Cell Regeneration in the Zebrafish Lateral Line
Mechanosensory hair cells within the zebrafish lateral line spontaneously regenerate after aminoglycoside-induced death. Exposure of 5-d-old larvae to 400 μm neomycin for 1 h results in death ofExpand
  • 197
  • 29
  • PDF
Auditory system development: primary auditory neurons and their targets.
The neurons of the cochlear ganglion transmit acoustic information between the inner ear and the brain. These placodally derived neurons must produce a topographically precise pattern of connectionsExpand
  • 506
  • 27
  • PDF
The Superior Olivary Nucleus and Its Influence on Nucleus Laminaris: A Source of Inhibitory Feedback for Coincidence Detection in the Avian Auditory Brainstem
Located in the ventrolateral region of the avian brainstem, the superior olivary nucleus (SON) receives inputs from nucleus angularis (NA) and nucleus laminaris (NL) and projects back to NA, NL, andExpand
  • 162
  • 24
  • PDF
In vitro analysis of optimal stimuli for phase-locking and time-delayed modulation of firing in avian nucleus laminaris neurons
Neurons of the avian nucleus laminaris (NL) provide a neural substrate for azimuthal sound localization. We examined the optimal stimuli for NL neurons to maintain high discharge rates, reliableExpand
  • 212
  • 19
  • PDF
Avian superior olivary nucleus provides divergent inhibitory input to parallel auditory pathways
The avian auditory brainstem displays parallel processing, a fundamental feature of vertebrate sensory systems. Nuclei specialized for temporal processing are largely separate from those processingExpand
  • 103
  • 18
  • PDF
Hair cell regeneration after acoustic trauma in adult Coturnix quail.
Recovery of hair cells was studied at various times after acoustic trauma in adult quail. An initial loss of hair cells recovered to within 5 percent of the original number of cells. Tritium-labeledExpand
  • 638
  • 17
Organization and development of brain stem auditory nuclei of the chicken: Tonotopic organization of N. magnocellularis and N. laminaris
  • E. Rubel, T. Parks
  • Biology, Medicine
  • The Journal of comparative neurology
  • 15 December 1975
Extracellular recordings of responses to tone‐burst stimulation were used to determine the tonotopic organization of n. magnocellularis (NM) and n. laminaris (NL) in hatchling chickens. NM cells showExpand
  • 261
  • 17
  • PDF
GABAergic terminals in nucleus maznocellularis and laminaris originate from the superior olivary nucleus
The auditory brainstem nuclei, angularis (NA), magnocellularis (NM), and laminaris (NL) of the chicken, Gallus, contain terminals that stain for antibodies against the inhibitory neurotransmitter,Expand
  • 135
  • 17
  • PDF