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orotidine

Known as: 3-ribofuranosylorotic acid, 6-carboxyuridine 
National Institutes of Health

Related topics

Related topics

4 relations
Orotidine/Creatinine:SRto:Pt:Urine:QnOrotidine:SCnc:Pt:Ser/Plas:Qnanalogs & derivatives

Broader (1)

Uridine

Papers overview

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2008
2008
Dissecting the total transition state stabilization provided by amino acid side chains at orotidine 5'-monophosphate decarboxylase: a two-part substrate approach.
Kinetic analysis of decarboxylation catalyzed by S154A, Q215A, and S154A/Q215A mutant yeast orotidine 5'-monophosphate… 
2002
2002
Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
The crystal structures of orotidine 5'-monophosphate decarboxylases from four different sources have been published recently… 
2000
2000
Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects.
Orotidine 5'-monophosphate shows a (15)N isotope effect of 1.0036 at N-1 for decarboxylation catalyzed by orotidine 5… 
1987
1987
The purification and preliminary characterization of UMP synthase from human placenta.
1976
1976
Purification, size, and properties of the complex of orotate phosphoribosyltransferase: orotidylate decarboxylase from mouse Ehrlich ascites carcinoma.
Highly Cited
1973
Highly Cited
1973
Kinetic properties and inhibition of orotidine 5'-phosphate decarboxylase. Effects of some allopurinol metabolites on the enzyme.
Abstract The 1- and 7-ribosyl 5'-phosphates of oxipurinol [4,6-dihydroxypyrazolo(3,4-d)pyrimidine] were enzymatically synthesized… 
Highly Cited
1972
Highly Cited
1972
Nephropathy, xanthinuria, and orotic aciduria complicating Burkitt's lymphoma treated with chemotherapy and allopurinol.
1968
1968
Biochemical mechanism of drug resistance. VII. Inhibition of orotic acid metabolism by 5-azacytidine in leukemic mice sensitive and resistant to 5-azacytidine.
1962
1962
Correlations of the biochemical and clinical effects of 6-azauridine in patients with leukemia
Highly Cited
1957
Highly Cited
1957
Conversion of uracil and orotate to uridine 5'-phosphate by enzymes in lactobacilli.
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