orotate

 
National Institutes of Health

Papers overview

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2009
2009
Orotate phosphoribosyltransferases (OPRT) catalyze the formation of orotidine 5'-monophosphate (OMP) from alpha-D… (More)
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2008
2008
In this paper we describe the new selection/counterselection vector pCS1966, which is suitable for both sequence-specific… (More)
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2007
2007
A new lactococcal plasmid, pDBORO, was isolated from the Lactococcus lactis subsp. lactis biovar diacetylactis strain DB0410… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Teriflunomide, a dihydro-orotate dehydrogenase inhibitor, has immunomodulatory effects, including the ability to… (More)
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2006
2006
PURPOSE We investigated whether the determination of orotate phosphoribosyltransferase (OPRT) and thymidylate synthase (TYMS… (More)
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Highly Cited
2005
Highly Cited
2005
The purine analogue, allopurinol, has been in clinical use for more than 30 years as an inhibitor of xanthine oxidase (XO) in the… (More)
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Highly Cited
2003
Highly Cited
2003
Activation of 5-fluorouracil into its nucleotides requires phosphorylation by three pathways involving orotate phosphoribosyl… (More)
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Highly Cited
2003
Highly Cited
2003
So far, the extremely halophilic archaeon Haloferax volcanii has the best genetic tools among the archaea. However, the lack of… (More)
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1998
1998
Leflunomide is currently in phase-III clinical trials for the treatment of rheumatoid arthritis. In this study, we have focused… (More)
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1979
1979
The conversion of dihydroorotate to orotate, one of the key reactions in the de novo pyrimidine biosynthetic pathway, has been… (More)
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