oleandrin

Known as: (3 beta,16 beta)-16-(acetyloxy)-3-((2,6-dideoxy-3-O-methyl-L-arabino-hexopyranosyl)oxy)-14-hydroxy card-20(22)-enolide 
A lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically binds to and inhibits the… (More)

Topic mentions per year

Topic mentions per year

1948-2017
024619482016

Papers overview

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2014
2014
We have previously shown that the botanical drug candidate PBI-05204, a supercritical CO2 extract of Nerium oleander, provides… (More)
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2007
2007
Lipid-soluble cardiac glycosides such as bufalin, oleandrin, and digitoxin have been suggested as potent agents that might be… (More)
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2007
2007
Common practice to evaluate the efficacy of any compound as drug is done in cell-based in vitro system followed by in vivo murine… (More)
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2006
2006
While certain cardiac glycoside compounds such as oleandrin, bufalin and digitoxin are known to be associated with potent… (More)
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2004
2004
Oleandrin, derived from the leaves of Nerium oleander, has been shown to possess anti-inflammatory and tumor cell growth… (More)
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2003
2003
Ceramide (N-acetyl-D-sphingosine), a second messenger for cell signaling induces transcription factors, like nuclear factor-kappa… (More)
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2002
2002
Cardiac glycosides such as digitoxin and ouabain have previously been shown to be selectively cytotoxic to tumor as opposed to… (More)
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2001
2001
Anvirzel is an extract of Nerium oleander currently undergoing Phase I clinical evaluation as a potential treatment for cancer… (More)
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Highly Cited
2000
Highly Cited
2000
Agents that can suppress the activation of nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) may be able to block… (More)
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1987
1987
In a fatal (cardiotoxic) case of oleander extract poisoning of a young female, ethanol extracts of blood and tissue homogenates… (More)
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