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olanexidine

Known as: 1-(3,4-dichlorobenzyl)-5-octylbiguanide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Biguanides

Narrower (1)

OPB-2045

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Aqueous olanexidine versus aqueous povidone-iodine for surgical skin antisepsis on the incidence of surgical site infections after clean-contaminated surgery: a multicentre, prospective, blinded…
BACKGROUND Surgical site infection (SSI) is the most common problem after surgery. Although several guidelines have indicated the… Expand
2019
2019
Evaluation of in Vitro Bactericidal Activity of 1.5% Olanexidine Gluconate, a Novel Biguanide Antiseptic Agent.
Recently, 1.5% olanexidine gluconate, a biguanide compounds, was launched as a new antiseptic agent in Japan. However, the… Expand
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2017
2017
Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys
Purpose. To determine the bactericidal efficacy of a new topical antiseptic for preoperative skin preparation, olanexidine… Expand
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2015
2015
Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic
ABSTRACT Olanexidine gluconate [1-(3,4-dichlorobenzyl)-5-octylbiguanide gluconate] (development code OPB-2045G) is a new… Expand
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Review
2015
Review
2015
Carbon–carbon bond cleavage and formation reactions in drug metabolism and the role of metabolic enzymes
Abstract Elimination of xenobiotics from the human body is often facilitated by a transformation to highly water soluble and more… Expand
2004
2004
Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes
1. The oxidative one-carbon cleavage reaction in the octyl side chain of olanexidine [l-(3,4-dichlorobenzyl)-5-octylbiguanide], a… Expand
2000
2000
In vitro characterization of the oxidative cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
The metabolism of olanexidine [1-(3,4-dichlorobenzyl)-5-octylbiguanide], a new potent biguanide antiseptic, was investigated in… Expand
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2000
2000
Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations.
The metabolism of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045), a new potent biguanide antiseptic, was investigated using… Expand
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1998
1998
Metabolism of 1-(3,4-dichlorobenzyl)-5-octylbiguanide in the dog.
1. The biotransformation of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045), a new potent biguanide antiseptic, was… Expand
1998
1998
High-performance liquid chromatography-electrospray tandem mass spectrometry for the measurement of 1-(3,4-dichlorobenzyl)-5-octylbiguanide in human serum.
1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) is a new biguanide antimicrobial agent currently in clinical use as a topical… Expand
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