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nucleolar fragmentation

The cell aging process that results in the nucleolus breaking down into fragments. [GOC:mah, PMID:9271578]
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
In the repeat array of ribosomal DNA (rDNA), only about half of the genes are actively transcribed while the others are silenced… 
2011
2011
It has been reported that nucleolar fragmentation is a part of the overall apoptotic morphology, however, it is currently obscure… 
Highly Cited
2000
Highly Cited
2000
For a number of organisms, the ability to withstand periods of nutrient deprivation correlates directly with lifespan. However… 
Highly Cited
1999
Highly Cited
1999
The cdk2 gene has been identified as a human cdc2/CDC28-related gene that encodes a protein kinase essential for the G1/S… 
Highly Cited
1997
Highly Cited
1997
The SGS1 gene of yeast encodes a DNA helicase with homology to the human WRN gene. Mutations in WRN result in Werner's syndrome… 
Highly Cited
1994
Highly Cited
1994
We have identified a set of genes that affect mRNA transport (mtr) from the nucleus to the cytoplasm of Saccharomyces cerevisiae… 
Highly Cited
1980
1970
1970