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nucleolar fragmentation

The cell aging process that results in the nucleolus breaking down into fragments. [GOC:mah, PMID:9271578]
National Institutes of Health

Papers overview

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2011
2011
In the repeat array of ribosomal DNA (rDNA), only about half of the genes are actively transcribed while the others are silenced… Expand
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2011
2011
It has been reported that nucleolar fragmentation is a part of the overall apoptotic morphology, however, it is currently obscure… Expand
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Highly Cited
2000
Highly Cited
2000
For a number of organisms, the ability to withstand periods of nutrient deprivation correlates directly with lifespan. However… Expand
Highly Cited
1999
Highly Cited
1999
The cdk2 gene has been identified as a human cdc2/CDC28-related gene that encodes a protein kinase essential for the G1/S… Expand
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Highly Cited
1997
Highly Cited
1997
The SGS1 gene of yeast encodes a DNA helicase with homology to the human WRN gene. Mutations in WRN result in Werner's syndrome… Expand
Highly Cited
1994
Highly Cited
1994
We have identified a set of genes that affect mRNA transport (mtr) from the nucleus to the cytoplasm of Saccharomyces cerevisiae… Expand
Highly Cited
1980
Highly Cited
1980
Abstract Cytological staining with silver nitrate is specific for a protein associated with chromosomal nucleolus organizer… Expand
1975
1975
Abstract The effects of MPB on the staining intensity of pyronine G, the fine structure of HeLa cell nucleoli and RNA synthesis… Expand
1972
1972
Immunofluorescence employing specific antibodies was used to detect nuclear and nucleolar macromolecules during the cell cycle in… Expand
1970
1970
It is known that in cultured cells treated with low doses of toyocamycin (1 μg/ ml) and less, there is a selective inhibition of… Expand