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nothapodytine B

Known as: mappicine ketone 
National Institutes of Health

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2 relations

Broader (2)

IndolizinesQuinolines

Papers overview

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2003
2003
An efficient approach to 3,4-disubstituted pyridin-2-ones. Formal synthesis of mappicine ketone.
Treatment of 3,4-dihydro-3-tosylpyridin-2-one 5 with sodium hydride and then alkyl halides gave various 3,4-disubstituted pyridin… 
2000
2000
New pyridone approach: total synthesis of mappicine ketone (nothapodytine B).
A novel synthesis of mappicine ketone, which possesses strong selective activity against the herpes viruses HSV-1 and HSV-2… 
2000
2000
Solution phase synthesis of libraries of polycyclic natural product analogues by cascade radical annulation: synthesis of a 64-member library of mappicine analogues and a 48-member library of…
An improved cascade radical annulation route to (+/-)-mappicine, (S)-mappicine, and mappicine ketone is reported. The route is… 
2000
2000
Unprecedented adducts formed by camptothecin and mappicine ketone with maleic anhydride under microwave irradiation
Camptothecin 11 is a naturally occurring novel pyrro lo-[3,4-b ]-quinoline alkaloid well-known for its potent antitumour activit… 
1998
1998
The first conversion of camptothecin to (S)-mappicine by an efficient chemoenzymatic method.
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