nocathiacin III

Presently, the arsenal of antimalarial drugs is limited and needs to be replenished. We evaluated the potential antimalarial… Expand

In order to improve aqueous solubility of nocathiacin I (1), a potent antibacterial agent, N-demethylation of the amino-sugar… Expand

Stereoselective reduction of dehydroalanine double bond in nocathiacin I afforded the primary amide 2. Enzymatic hydrolysis of… Expand

The synthesis and antibacterial activity of a series of nocathiacin I derivatives (4-20) containing polar water solubilizing… Expand

Several nocathiacin I analogues (4-35) were synthesized and evaluated for their antibacterial activity. Most of these semi… Expand