nocathiacin III

Presently, the arsenal of antimalarial drugs is limited and needs to be replenished. We evaluated the potential antimalarial… (More)

In order to improve aqueous solubility of nocathiacin I (1), a potent antibacterial agent, N-demethylation of the amino-sugar… (More)

We report here the observation of O-H...N hydrogen-bond (1h)J(N,OH) scalar coupling in a biologically active natural product. The… (More)

The synthesis and antibacterial activity of a series of nocathiacin I derivatives (4-20) containing polar water solubilizing… (More)

Several nocathiacin I analogues (4-35) were synthesized and evaluated for their antibacterial activity. Most of these semi… (More)