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nizofenone

Known as: 1-(2-(2-chlorobenzoyl)-4-nitrophenyl)-2-(diethylaminomethyl)imidazole 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

Anti-Arrhythmia AgentsImidazolesNeuroprotective Agents

Narrower (2)

Y-9179nizofenone fumarate

Papers overview

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1996
1996
Volume‐sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U‐138MG)
Glial cell swelling in hypotonic media activates an anionic channel that was found previously to be permeable to amino acids. It… 
Review
1993
Review
1993
Brain protection against ischemic injury by nizofenone.
Ischemic brain injury is induced in a complex and multifactorial pathogenic cascade; but the fundamental mechanism is the… 
1988
1988
Brain protection against oxygen deficiency by nizofenone.
The cerebral protective effect of nizofenone against tissue oxygen deficiency was investigated in mice. Treating mice with… 
Highly Cited
1986
Highly Cited
1986
Nizofenone administration in the acute stage following subarachnoid hemorrhage. Results of a multi-center controlled double-blind clinical study.
A multi-center controlled double-blind clinical study was carried out to evaluate the effects of nizofenone in patients with… 
1986
1986
[Treatable ischemic neuronal damage in the gerbil hippocampus].
The Mongolian gerbil is known to develop delayed neuronal death in the hippocampus following brief forebrain ischemia (Brain Res… 
Highly Cited
1985
Highly Cited
1985
Biphasic Liberation of Arachidonic and Stearic Acids During Cerebral Ischemia
Abstract: The mode of free fatty acid (FFA) liberation from the mouse brain during ischemia was investigated at various times… 
Highly Cited
1984
Highly Cited
1984
The Protective Effect of Combined Administration of Anti-Oxidants and Perfluorochemicals on Cerebral Ischemia
We previously published results of investigations which indicated that the combination of mannitol, which acts as a free radical… 
1983
1983
A double-blind clinical evaluation of the effect of Nizofenone (Y-9179) on delayed ischemic neurological deficits following aneurysmal rupture.
The effect of Nizofenone (Y-9179), a vertebral protective agent, on delayed ischemic neurological deficits following subarachnoid… 
1982
1982
Mechanisms of cerebral protection by pentobarbital and nizofenone correlated with the course of local cerebral blood flow changes.
The effects of delayed administration of pentobarbital and a novel imidazole derivative (Nizofenone or Y-9179) on the infarction… 
1981
1981
Cerebral Protective Effect and Radical Scavenging Action
Abstract The role of radical scavenging action in cerebral protective effect of drugs was investigated in vitro. Incubation of… 
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